A classic in the area of organic synthesis, Strategies and Tactics in Organic Synthesis provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a second-hand analysis, we are given stories that vividly demonstrate the power of the human endeavour known as organic synthesis and the creativity and tenacity of its practitioners. First hand accounts of each project tell of the excitement of conception, the frustration of failure and the joy experienced when either rational thought and/or good fortune give rise to successful completion of a project. In this book we learn how synthesis is really done and are educated, challenged and inspired by these stories, which portray the idea that triumphs do not come without challenges. We also learn that we can meet challenges to further advance the science and art of organic synthesis, driving it forward to meet the demands of society, in discovering new reactions, creating new designs and building molecules with atom and step economies that provide solutions through function to create a better world. - Personal accounts of research in organic chemistry. - Written by internationally renowned scientists. - Details state of the art organic synthesis.
This book series shows how synthesis is really done, and we are educated, challenged and inspired by these accounts, which portray the idea that triumphs do not come without challenges.
This is a unique account of the synthesis of organic molecules. All of the contributors are acknowledged experts in organic synthesis.
(b)Kummer DA, Chain WJ, Morales MR, Quiroga O, Myers AG. JAm Chem Soc. 2008;130:13231–13233. 3. For selected references, see: (a) Myers, A. G.; Yang, B. H.; Chen, H.; McKinstry, L.; Kopecky, D. J.; Gleason, J. L. J. Am. Chem. Soc.
This title provides a forum for investigators to discuss their approach to the science and art of organic synthesis in a unique way.
This account describes the total synthesis of the title compound, an antimitotic bicyclic peptide.
Chem. Int. Ed. 1999, 38, 2012–2014. L. A. Paquette, M. Vazeux, Tetrahedron Lett. 1981, 22, 291–294. H. E. Simmons, III, J. E. Maggio, Tetrahedron Lett. 1981, 22, 287–290. (a) F. E. McDonald, X. Wang, B. Do, K. I. Hardcastle, Org. Lett.
Addition of halogen and nucleophiles to conjugated 1,3-enynes in a 1,4-fashion produces a chiral allene and a stereogenic center.
This is a unique account of the synthesis of organic molecules. All of the contributors are acknowledged experts in organic synthesis.
Described herein is an account of my laboratory’s entry into the magnificent field of complex alkaloid total synthesis, spanning the development of novel methods for quickly assembling polycyclic frameworks through the total synthesis of ...
Synthesis targets for alkynyliodonium salt chemistry. In a second thrust, highlighting the value of stereospecificity in alkylidenecarbene C-H insertions (attribute # 2) called for a target that featured a demanding cyclopentyl ...