The finding by Emil Fischer that glucose and fructose on treatment with phenylhydrazine gave the identical osazone led him to the elucidation of stereochemistry of carbohydrates. Since then, progress in the field of carbohydrates has been amazing with the unraveling their basic structure, biosynthesis, immunology, functions, and clinical uses, for pure carbohydrates and for protein-linked carbohydrates (glycoproteins and proteoglycans). The chapters in Carbohydrate Chemistry, Biology and Medical Applications present a logical sequence leading from the chemistry and biochemistry of carbohydrates, followed by their role in various pathological conditions, to carbohydrates as potential therapeutic and diagnostic agents. This book offers a detailed panoramic review of the chemistry and biology of carbohydrates for chemists, biologists and health professionals. Each chapter is authored by contributors expert in the particular area of research. Explains how carbohydrates are important to life Details the chemistry, biology and medical aspects of carbohydrates Interdisciplinary and international team of authors
There are practical examples on the development of carbohydrate-based pharmaceuticals and polymers for commercial use. The text also emphasizes the role of carbohydrates as key elements in modern molecular recognition processes.
National Research Council (US) Committee on Assessing the Importance and Impact of Glycomics and Glycosciences (2012) Transforming Glycoscience: A Roadmap for the Future ...
Providing a worldwide perspective on this broad area, and providing examples of therapeutics already developed using these methods, this book provides a comprehensive introduction, discussion and update on this fast developing field for ...
Recently, a new ecocatalyst, called Eco-Pd, prepared by a new process based on biosorption technology and using roots from aquatic and wetlands rich in lignins and wastes also rich in lignins, was very successful for a green and ...
Various 2,3-epoxypyranosides such as 133 can be converted into furanosides directly by simple heating under reflux in toluene containing lithium bromide and N,N-tetramethylurea [132] (Scheme 21). Usually, the more stable 3-C-formyl ...
The text is accompanied by over 2000 figures, chemical structures and reaction schemes and more than 9000 references. The accompanying CD-ROM enables, besides text searches, searches for structures, schemes, and other information.
In the presence of a mineral or Lewis acid catalyst, this “normal” addition process is generally accompanied or replaced by concurrent allylic rearrangement (63, ... Lewis 0 9 *: —#—- RCO '' —- so e) * -> 0 H6) : = 6 0 +/ .
This book contains contributions from interdisciplinary scientists to collectively address the issue of targeting carbohydrate recognition for the development of novel therapeutic and diagnostic agents.
In 2010, the National Academy of Sciences, USA, published an excellent proposal designated as Transforming Glycoscience: A Roadmap for the Future and gave a strong impact on glycoscientists and stakeholders and funding agencies ...
Therefore the editors have drawn together in this three volume set the complete and up-to-date information on glycostructures, their chemistry and chemical biology, and present them in the form of a comprehensive and strictly systematic ...