Signal Transduction, 2e, is a thorough, well-illustrated study in cellular signaling processes. Beginning with the basics, this book shows how cells respond to external cues, hormones, growth factors, cytokines, cell surfaces, etc., and further instructs how these inputs are integrated. Instruction continues with up-to-date, inclusive coverage of intracellular calcium, nuclear receptors, tyrosine protein kinases and adaptive immunity, and targeting transduction pathways for research and medical intervention. Signal Transduction, 2e, serves as an invaluable resource for advanced undergraduates, graduate researchers, and established scientists working in cell biology, pharmacology, immunology, and related fields. Up-to-date, inclusive coverage of targeting transduction pathways for research and medical intervention In-depth coverage of nuclear receptors, including steps in isolation of steroid hormones and the discovery of intracellular hormone receptors; tyrosine protein kinases and adaptive immunity; and intracellular calcium Extensive conceptual color artwork to assist with comprehension of key topics Instrumental margin notes highlight milestones in signaling mechanisms
This second edition represents an update to that previous work with an emp- sis on new methodologies that have developed in the last few years.
A major contribution to the development of the novel pharmacotherapeutics targeting downstream events in the cascade of second, third, and fourth messengers, it will serve experimental and clinical neuroscientists as today's best and most ...
This latest volume, An Introduction to Cellular Signal Transduction, complements the previous monographs in the series and brings to the fore recent developments in the field of biochemical communication.
Signal transduction pathways are molecular circuits that define how cells communicate with each other and respond to their environment.
A variety of powerful techniques for monitoring and analysing events during signal transduction at the single cell level are described in this lab manual.
Written for those with a basic understanding of molecular and cell biology, the book will be of particular interest to graduate students and researchers who need to grasp the principles of signal transduction.
... organization of signaling pathways. Trends Biochem Sci 39:457–464. Tyson JJ, Chen KC & Novak B (2003) Sniffers, buzzers, toggles and blinkers: dynamics of regulatory and signaling pathways in the cell. Curr Opin Cell Biol 15:221–223.
Beginning with an overview and methods for measuring compounds that affect redox and the redox state of cells, the book continues with reviews of the use of GFP and its derivatives, methods to study the impact of changing redox on proteins, ...
Comprehensive and highly practical, Xenopus Protocols: Cell Biology and Signal Transduction serves perfectly to instruct novices in the use of Xenopus oocytes/extracts, as well as seasoned investigators interested in developing novel models ...
The chapters in this volume are the Proceedings of the Satellite Symposium of the XVIth World Congress of the International Society for Heart Research on `Signal Transduction in Normal and...