In the nearly 60 years since Watson and Crick proposed the double helical structure of DNA, the molecule of heredity, waves of discoveries have made genetics the most thrilling field in the sciences. The study of genes and genomics today explores all aspects of the life with relevance in the lab, in the doctor’s office, in the courtroom and even in social relationships. In this helpful guidebook, one of the most respected and accomplished human geneticists of our time communicates the importance of genes and genomics studies in all aspects of life. With the use of core concepts and the integration of extensive references, this book provides students and professionals alike with the most in-depth view of the current state of the science and its relevance across disciplines. Bridges the gap between basic human genetic understanding and one of the most promising avenues for advances in the diagnosis, prevention and treatment of human disease. Includes the latest information on diagnostic testing, population screening, predicting disease susceptibility, pharmacogenomics and more Explores ethical, legal, regulatory and economic aspects of genomics in medicine. Integrates historical (classical) genetics approach with the latest discoveries in structural and functional genomics
How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project.
We also want to thank Catherine Mori who co-authored the original edition of this book and was instrumental in creating its format. We are grateful to everyone whose artwork appears in this volume. While we ourselves created many of the ...
The 5th edition continues to build upon the integration of Mendelian and molecular principles, providing students with the links between the early understanding of genetics and the new molecular discoveries that have changed the way the ...
Basic information about these molecules and their gene content, based on a reference genome that does not represent the sequence of any specific individual, are provided in the following table.This book is an excellent overview of the human ...
The Book of Genes & Genomes presents a concise overview of the advances in genetics and genomics and provide the unfamiliar reader with a succinct description of many of the applications and implications of this field.
Angela Christiano , a dermatologist at Columbia University in New York , studies rare families with alopecia universalis , a recessively inherited disease in which affected individuals have virtually no hair follicles and no scalp or ...
This book provides a detailed evidence-based overview of the latest developments in how the structure of the human genome is relevant to the health professional.
Therefore, only a few topics are chosen, which are of great interest to molecular geneticists. This volume is intended for advanced graduate students who would wish to keep abreast with the most recent trends in genome biology.
This book furnishes readers with a good summary of current research in the field. This book reviews the human genome from an evolutionary perspective.
Thoroughly updated and restructured, this brand new edition uses both a classic didactic approach to teach basic genetic concepts and a problem-based approach to demonstrate the clinical applications of genetics in medical practice.