Correlative Light and Electron MIcroscopy
- ISBN-10
- 0123914388
- ISBN-13
- 9780123914385
- Category
- Science
- Pages
- 460
- Language
- English
- Published
- 2012-10-23
- Publisher
- Academic Press
Description
The combination of electron microscopy with transmitted light microscopy (termed correlative light and electron microscopy; CLEM) has been employed for decades to generate molecular identification that can be visualized by a dark, electron-dense precipitate. This new volume of Methods in Cell Biology covers many areas of CLEM, including a brief history and overview on CLEM methods, imaging of intermediate stages of meiotic spindle assembly in C. elegans embryos using CLEM, and capturing endocytic segregation events with HPF-CLEM. Covers many areas of CLEM by the best international scientists in the field Includes a brief history and overview on CLEM methods
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