Synthesis of Best-Seller Drugs is a key reference guide for all those involved with the design, development, and use of the best-selling drugs. Designed for ease of use, this book provides detailed information on the most popular drugs, using a practical layout arranged according to drug type. Each chapter reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and synthesis. Of high interest to all those who work in the captivating areas of biologically active compounds and medicinal drug synthesis, in particular medicinal chemists, biochemists, and pharmacologists, the book aims to support current research efforts, while also encouraging future developments in this important field. Describes methods of synthesis, bioactivity and related drugs in key therapeutic areas Reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and more Presents a practical layout designed for use as a quick reference tool by those working in drug design, development and implementation
This text features contributions from seventeen leading medicinal and process chemists who show you how it is done.
This is followed by a detailed discussion of methods for their synthesis. Of the thousands of drugs existing on the pharmaceutical market, the book mainly covers generic drugs that are included in the WHO’s Essential List of Drugs.
Authored by four of the pharmaceutical industry's most respected scientists, this timely volume: Focuses on the processes that resulted in high-profile drugs including Lipitor, Celebrex, Viagra, Gleevec, Nexium, Claritin, and over a dozen ...
The classic reference on the synthesis of medicinal agents -- now completely updated The seventh volume in the definitive series that provides a quick yet thorough overview of the synthetic routes used to access specific classesof ...
Curran, A. C. W.; Shepherd, R. G.; J. Chem. Soc., Perkin Trans]. 1976, 983. Lesher, G. Y.; Froelich, E. J .; Gruett, M. D.; Bailey, J. H.; Brundage, R. P.; J. Med. Chem. 1962, 5, 1063. Kaminsky, D.; Meltzer, R. I.; J. Med. Chem.
An Introduction to Drug Synthesis explores the central role played by organic synthesis in the process of drug design and development - from the generation of novel drug structures to the improved efficiency of large scale synthesis.
(a) Senn-Bilfinger, J.; Kruger, U.; Sturm, E.; Figala, V.; Klemm, K.; Kohl, B.; Rainer, G.; Schaefer, H.; Blake, T.J.; Darkin, D.W.; Ife, R.J.; Leach, C.A.; Mitchell, R.C.; Pepper, E.S.; Salter, C.J.; Viney, N.J.; Huttner, G.; Zsolnai, ...
This book will allow students to see how the organic chemistry taught in undergraduate courses is applied by medicinal chemists in industry.
Following Contemporary Drug Synthesis and The Art of Drug Synthesis (Wiley, 2004 and 2007), two well-received works, is this new book that demystifies the process of modern drug discovery for practitioners and students.
What are the current industrial research problems and how can they be resolved in an industrial setting? This book highlights key methods that have real impact in drug discovery and facilitate delivery of drug molecules.