Alzheimer's Disease: Lifecourse Perspectives on Risk Reduction summarizes the growing body of knowledge on the distribution and causes of Alzheimer’s disease (AD) in human populations, providing the reader with knowledge on how we define the disease and what its risk and protective factors are in the context of a life-course approach. At the conclusion of the book, the reader will understand why Alzheimer’s disease likely begins at conception, then progresses through early-life and adult risk factors that ultimately impact the balance between pathologic insults in the brain and the ability of the brain to modify disease symptoms. In contrast to edited volumes that may have little cohesion, this book focuses on an integrated life-course approach to the epidemiology of dementia, in particular, Alzheimer’s disease. Reviews the current science surrounding Alzheimer’s disease Provides a primer of foundational knowledge on the disease's epidemiology and biostatistics Utilizes a life-course approach, providing a novel and integrated view of the evolution of this illness from genes to brain reserve Uses the ‘threshold model’—a theory first described by Dr. Mortimer and widely accepted today—which incorporates the idea of risk factors for the pathology and expression of the disease Proposes that improving brain health through modifiable behaviors can delay disease onset until a later age Examines the future of prevention of Alzheimer’s disease, a subject of great current interest
This book is particularly designed to assist physicians and other health-care professionals in the evaluation, assessment, and treatment of individuals with AD. At the same time, by illuminating the basic scientific background, we hope to ...
This book brings together many of the world's leading scientists researching aluminium and life and contains their critical summaries on the known facts about aluminium toxicity in man and to offer an opinion on the implications of this ...
The first book to provide a comprehensive look at what it's like to have dementia and the subjective experience of living with progressive memory loss. Few families are untouched by Alzheimer's disease or a related dementia.
Part of the Oxford Neurology Library series, this second edition of Alzheimer's Disease is a succinct and practical introduction to the diagnosis, evaluation and management of Alzheimer's disease.
This is the problem posed to a group of our colleagues who are using state-of-the-art neural imaging methods in patients and in animal models to illuminate the natural history of the disease – in the living brain.
The knowledge contained in this volume should help to accelerate ongoing attempts to develop novel treatments for Alzheimer's disease and related disorders.
This is a conservative figure, however, because many persons with dementia spend their last few years in a nursing home at an average 'cost of $22,000 per year, and some spend from 10 to 15 years in a nursing home, for a total cost of $220 ...
Steven R. Sabat mines a large body of research to convey the genetic and biological aspects of Alzheimer's disease, its clinical history, and, most significantly, to reveal the subjective experience of those with Alzheimer's or dementia.
This new volume of Advances in Pharmacology explores the Current State of Alzheimer's Disease Research and Therapeutics.
This book, written by the most outstanding scientists in this new filed, is the first presentation of results concerning the implications of apolipoprotein E on the genetics, cell biology, neuropathology, biochemistry, and therapeutic ...