The Organic Chemistry of Enzyme-catalyzed Reactions
- ISBN-10
- 0126437459
- ISBN-13
- 9780126437454
- Category
- Science
- Pages
- 717
- Language
- English
- Published
- 2000
- Publisher
- Academic Press
- Author
- Richard B. Silverman
Description
Written for advanced undergraduate and graduate students as well as professionals in organic and medicinal chemistry and biochemistry, this unique text illuminates the "black box" of enzyme-catalyzed reactions by showing how enzymes are simply highly efficient organic chemists. Enzyme-catalyzed reactions are essential for the design of enzyme inhibitors in the pharmaceutical and agricultural industries, and of growing importance for process development in the chemical and biotechnology industries. Following a general introduction to the role of enzymes as catalysts, each chapter describes the organic reaction mechanisms that are used by enzymes to catalyze a particular family of organic transformations. The compilation includes a vast number of drawings to illustrate structures and mechanisms, and focuses on one or two examples of enzymes that catalyze the particular chemistry for that transformation. The Organic Chemistry of Enzyme-Catalyzed Reactions is not a book on enzymes, but rather the general mechanisms used by enzymes. Extensive references refer to the many experiments that have helped to elucidate enzyme mechanisms. Chemical model studies as an aid in mechanistic studies are also discussed, as are the design of haptens and the generation of catalytic antibodies ("designer enzymes"). Problem sets and solutions are provided to check the reader's understanding of the principles described. * Shows how enzyme-catalyzed reactions are simply efficient organic reaction * Emphasizes the connection between organic reaction mechanisms and enzyme mechanisms * Explains how enzymes can accelerate the rates of chemical reactions withhigh specificity * Uses selected enzymes to demonstrate general mechanisms of enzyme-catalyzed reaction * Illustrated with a vast array of clearly drawn structures, schemes, and figures * Includes an extensive bibliography on enzyme mechanisms * Describes approaches to the design of enzyme inhibitors * Covers catalytic antibody design and mechanisms * Provides problem sets and solutions for each chapter * Written in an informal and engaging style
Get the book
Similar books
-
Chemistry: An Introduction to General, Organic and Biological Chemistry
By Karen C. TimberlakeThis new edition introduces more problem-solving strategies and new conceptual and challenge problems. Also, each Chapter Review has been enhanced with Learning Goals to reinforce the mastery of concepts for students.
-
Chemistry: An Introduction to General, Organic, and Biological Chemistry
By Karen TimberlakeThis laboratory manual contains 42 experiments for the standard sequence of topics in general, organic, and biological chemistry.
-
Basic Chemistry
By Karen C. TimberlakeThe book guides students through basic chemistry problem solving with engaging visuals and a focus on developing the math skills necessary to be successful in the course.
-
General, Organic, and Biological Chemistry: Structures of Life, eBook, Global Edition
By Karen C. TimberlakeThe full text downloaded to your computer With eBooks you can: search for key concepts, words and phrases make highlights and notes as you study share your notes with friends eBooks are downloaded to your computer and accessible either ...
-
Basic Chemistry
By Karen C. Timberlake, William E. TimberlakeBasic Chemistry
-
Basic Chemistry, Books a la Carte Edition
By Karen C. TimberlakeBasic Chemistry, Books a la Carte Edition
-
Essential Laboratory Manual for General, Organic and Biological Chemistry
By Karen C. TimberlakeEssential Laboratory Manual for General, Organic and Biological Chemistry
-
Basic Chemistry, Global Edition
By Karen C. Timberlake, Bill TimberlakeThe main objective in writing this text is to make the study of chemistry an engaging and a positive experience for students by relating the structure and behaviour of matter to real life.
-
General, Organic, and Biological Chemistry: An Integrated Approach
By Karen C. Timberlake, Laura D. Frost, Todd S. DealThe eText pages look exactly like the printed text, and include powerful interactive and customization functions. This is the product access code card for MasteringChemistry with Pearson eText and does not include the actual bound book.
-
Chemistry: An Introduction to General, Organic, and Biological Chemistry
By Karen C. TimberlakeHealth, Environmental, and Green Chemistry Notes throughout the text relate chemistry chapters to real-life topics in health, the environment, and medicine that are interesting and motivating to students.