Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components: Chapter 3. Bioactivity of Plant Constituents against Vancomycin-Resistant Enterococci

Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components: Chapter 3. Bioactivity of Plant Constituents against Vancomycin-Resistant Enterococci
ISBN-10
0128066741
ISBN-13
9780128066744
Series
Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components
Category
Medical
Pages
296
Language
English
Published
2013-05-24
Publisher
Elsevier Inc. Chapters
Author
Victor Kuete

Description

The development of vancomycin resistance by some microbial strains has made the treatment of some infections more difficult and, in many cases, impossible. Although the search for new drugs against vancomycin-resistant organisms has been very successful, resistance can arise against many of these compounds. Natural products are an invaluable source of a diversity of biologically active compounds for addressing the challenges facing drug development initiatives to combat vancomycin-resistant enterococcal infections. Despite the fact that scientific data on plant metabolites active against vancomycin-resistant enterococci remain scarce, some compounds (including terpenoids and phenolics) have been reported to have inhibitory effects at various levels. This chapter describes the state of the art of research into plant bioactive metabolites against vancomycin-resistant enterococci, highlighting the hit compounds.

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