Invertebrate Learning and Memory: Chapter 31. Memory Phases and Signaling Cascades in Honeybees

Invertebrate Learning and Memory: Chapter 31. Memory Phases and Signaling Cascades in Honeybees
ISBN-10
0128071796
ISBN-13
9780128071793
Series
Invertebrate Learning and Memory
Category
Medical
Pages
600
Language
English
Published
2013-06-18
Publisher
Elsevier Inc. Chapters
Author
Uli Müller

Description

Appetitive associative conditioning in the honeybee Apis mellifera provides the basis to address the molecular link between training parameters and memory focusing on the induction and maintenance of memory phases. Special techniques developed to monitor and manipulate signaling cascades at high temporal and spatial resolution uncovered the critical role of learning-induced dynamic changes of signaling cascades and their contribution to distinct aspects of memory formation. This analysis demonstrated an important role of cAMP- and Ca2+-dependent signaling processes acting in parallel. Both reside in the antennal lobes and are critical for the induction of long-term memory and the maintenance of midterm memory.

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