Principles and Applications of Clinical Mass Spectrometry: Small Molecules, Peptides, and Pathogens is a concise resource for quick implementation of mass spectrometry methods in clinical laboratory work. Focusing on the practical use of these techniques, the first half of the book covers principles of chromatographic separations, principles and types of mass spectrometers, and sample preparation for analysis; the second half outlines the main applications of this technology within clinical laboratory settings, including determination of small molecules and peptides, as well as pathogen identification. A thorough yet succinct guide to using mass spectrometry technology in the clinical laboratory, Principles and Applications of Clinical Mass Spectrometry: Small Molecules, Peptides, and Pathogens is an essential resource for chemists, pharmaceutical and biotech researchers, certain government agencies, and standardization groups. Provides concrete examples of the main applications of mass spectrometry technology Describes current capabilities of the LC- and MS-based analytical methods Details methods for successful analytical work in the field
These chapters also include recommendations for maintaining continuity of quality in testing. The later parts of the book focuses on specific types of assays (therapeutic drugs, Vitamin D, hormones, etc.).
This issue of Clinics in Laboratory Medicine, Guest Edited by Nigel Clarke, MD, and Andrew Hoofnagle, MD, will focus on Mass Spectrometry, with topics including: Proteins; Peptides; Small Molecules: Toxicology; Small Molecules: Diagnostics; ...
Clinical Biochemistry: Principles, Methods, Applications: Mass Spectrometry
It will go a long way to help the utilization of mass spectrometry in medicine. The book comprises five parts. A general overview is followed by a description of the basic sampling and separation methods in analytical chemistry.
Journals Each clinical speciality has its own journals, often covering new mass spectrometry assay procedures, but those listed here ... De Hoffman, E. and Stroobant, V. (2007) Mass Spectrometry: Principles and Applications, 3rd edn.
In these cases, MSI analysis can be used to assist the pathologist in making a more accurate diagnosis. ... gives great insight into the metastatic process and may lead to the discovery of novel biomarkers for diagnosis and treatment of ...
Comprehensive in scope, this vital text: -Sets the standard on an important and emerging ionization technique -Thoroughly discusses all the relevant aspects from instrumentation to applications -Helps in solving numerous analytical problems ...
Offers a complete overview of the principles, theories and key applications of modern mass spectrometry in this introductory textbook. Following on from the highly successful first edition, this edition is...
This volume would be of interest to anyone who works in or studies analytical chemistry, omics sciences (including metabolomics), pharmacokinetics, forensic science or drug analysis.
[5] R.F. Clarke, Insecticides: organic phosphorus compounds and carbamates, in: N.E. Flomenbaum, L.R. Goldfrank, R.S. Hoffman, M.A. Howland, N.A. Lewin, L.S. Nelson (Eds.), Goldfrank's Toxicologic Emergencies, eighth ed, McGraw-Hill, ...