Synthetic and Enzymatic Modifications of the Peptide Backbone

Synthetic and Enzymatic Modifications of the Peptide Backbone
ISBN-10
0128212543
ISBN-13
9780128212547
Category
Science
Pages
640
Language
English
Published
2021-07-27
Publisher
Academic Press

Description

Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Methods of Enzymology series Updated release includes the latest information on the Synthetic and Enzymatic Modifications of the Peptide Backbone

Similar books

  • Bio-Synthetic Hybrid Materials and Bionanoparticles: A Biological Chemical Approach Towards Material Science
    By Alexander Boker, Patrick van Rijn

    The first section of the book focusses on the design and synthesis of different bionanoparticles and hybrid structures including the use of genetic modification as well as by organic synthesis.

  • Synthetic Biology
    By Luc Brunsveld, Maxim Ryadnov, Hiroaki Suga

    Then techniques are discussed yielding proteins with natural synthetic modifications. Examples discussed include nonsense ... Many enzymatic proteins are able to modify peptide side chains or the backbone. These PTMs are a way for the ...

  • Glycopeptides and Glycoproteins: Synthesis, Structure, and Application
    By Valentin Wittmann

    These building blocks can then be introduced into the growing peptide chain to produce O-linked glycopeptides with one or several attachment sites of the carbohydrate to the peptide backbone. Chemo-enzymatic modifications can also occur ...

  • Synthetic Peptides: A User's Guide
    By Gregory A. Grant

    carboxypeptidases like angiotensin converting enzyme (ACE), which cleave the C-terminal dipeptide from a peptide chain. ... Introduction of steric bulk along the peptide backbone by substitution of methyl groups for o-hydrogens or amide ...

  • Lasso Peptides: Bacterial Strategies to Make and Maintain Bioactive Entangled Scaffolds
    By Yanyan Li, Séverine Zirah, Sylvie Rebuffat

    Lasso peptides form a growing family of fascinating ribosomally-synthesized and post-translationally modified peptides produced by bacteria.

  • Peptide and Peptidomimetic Therapeutics: From Bench to Bedside
    By Nir Qvit, Samuel J.S. Rubin

    14.2.2 Synthetic Synthetic peptides are exceptional protein mimics. Synthetic peptides can be generated with diverse chemical modifications, including the introduction of nonnatural amino acids or modification of the peptide backbone.

  • Engineering Synthetic Metabolons: From Metabolic Modelling to Rational Design of Biosynthetic Devices
    By Lars M. Voll, Zoran Nikoloski

    Synthetic peptides have proven an excellent type of molecule for the mimicry of protein sites because such peptides can be ... of a large range of non-proteinogenic amino acids as well as the modification of the peptide backbone.

  • Micro- and Nanotechnology in Vaccine Development
    By Istvan Toth, Mariusz Skwarczynski

    This book provides a comprehensive overview of how use of micro- and nanotechnology (MNT) has allowed major new advance in vaccine development research, and the challenges that immunologists face in making further progress.

  • Combinatorial Chemistry: Synthesis, Analysis, Screening
    By Günther Jung

    ... Discovery and Screening 14.1.1 A Rationale for New Methods in Drug Discovery Combinatorial chemistry has been one ... high-throughput screening (HTS) will be a key factor in realizing the potential of new drug discovery strategies ...

  • Radical SAM Enzymes

    Radical SAM Enzymes, Volume 606, the latest release in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on the Characterization of the glycyl radical enzyme choline ...