The Epstein-Barr virus (EBV) was discovered in 1964. At the time, the very idea of a virus underlying a cancer was revolutionary. Cancer is, after all, not catching. Even now, the idea of a virus causing cancer surprises many people. But Epstein-Barr, named after its discoverers, Sir Anthony Epstein and Dr Yvonne Barr, is fascinating for other reasons too. Almost everyone carries it, yet it is only under certain circumstances that it produces disease. It has been associated with different, apparently unrelated, diseases in different populations: Burkitt's Lymphoma, producing tumours in the jaw, in African children; a nasal tumour in China; glandular fever in Europe and the USA; and the majority of cases of Hodgkin's Disease everywhere. This book tells the story of the discovery of the virus, and the recognition of its connection with these various diseases - an account that spans the world and involves some remarkable characters and individual stories.
This book, in a new, extensively updated edition, covers viral infection, virus-induced inflammation and tissue injuries, viral epidemiology, oncogenic mechanisms, and current and emerging preventive and therapeutic strategies in detail.
By showcasing the scientists themselves, the book makes for an unusually accessible journey through the history of science.
In this book, outstanding researchers from the US and Japan review recent progress in Epstein-Barr virus research. Most people carry EBV in memory B-cells in a latent stage.
George H. Christian sent his son, George Chase Christian, to Phillips Academy, an exclusive high school in Andover, Massachusetts, that served as a preparatory “farm team” for Yale University. Phillips Academy, founded in 1778, ...
Pickering, Andrew. The Cybernetic Brain. Chicago: University of Chicago Press, 2009. Pickstone, John V. “Contested Cumulations: Configurations of Cancer Treatments through the Twentieth Century.
This volume is dedicated to Baruch Blumberg, an outstanding scientist and recipient of the Nobel Prize for the discovery of the hepatitis B virus, who was also the author of one of the chapters.
It then explores several of these viruses in detail, including: Human T-cell leukemia virus type 1 (HTLV-1) Hepatitis C virus (HCV) Epstein–Barr virus (EBV) Human papilloma virus (HPV) Human herpes virus 8 (HHV-8)/Kaposi’s sarcoma ...
Viruses and Human Cancer provides a comprehensive review of the seven currently known human tumor viruses and their associated cancers with an emphasis on epidemiology, clinicopathologic features, and pathogenesis.
Organized into seven parts, this book begins with a discussion on the host-cell-virus relationships. Some chapters follow that discuss the comparative aspects of DNA and RNA oncogenic viruses.
This volume focuses on virus-host cell interactions, cellular genes acquired or modulated by viruses, the pathological effects of these interactions, and therapeutic interventions.