A Primer of Population Genetics and Genomics has been completely revised and updated to provide a concise but comprehensive introduction to the basic concepts of population genetics and genomics. Recent textbooks have tended to focus on such specialized topics as the coalescent, molecular evolution, human population genetics, or genomics. This primer bucks that trend by encouraging a broader familiarity with, and understanding of, population genetics and genomics as a whole. The overview ranges from mating systems through the causes of evolution, molecular population genetics, and the genomics of complex traits. Interwoven are discussions of ancient DNA, gene drive, landscape genetics, identifying risk factors for complex diseases, the genomics of adaptation and speciation, and other active areas of current research. The principles are illuminated by numerous examples from a wide variety of animals, plants, microbes, and human populations. The approach also emphasizes learning by doing, which in this case means solving numerical or conceptual problems. The rationale behind this is that the use of concepts in problem-solving lead to deeper understanding and longer knowledge retention. This accessible, introductory textbook is aimed principally at students of various levels and abilities (from senior undergraduate to postgraduate) as well as practising scientists in the fields of population genetics, ecology, evolutionary biology, computational biology, bioinformatics, biostatistics, physics, and mathematics.
This accessible primer has been completely revised and updated to provide a concise but comprehensive introduction to the basic concepts of population genetics and genomics.
This book introduces, in an accessible way, the bare essentials of the theory and practice of molecular population genetics.
The four chapters of the book address genetic variation, the causes of evolution, molecular population genetics, and the genetic architecture of complex traits.
Authored by leading experts, this seminal text presents a straightforward and elementary account of coalescent theory, which is a central concept in the study of genetic sequence variation observed in a population.
This book focuses on applying the hugely popular R software specifically to the field, offering an accessible, step-by-step guide to tackling the challenges of achieving effective data interpretation and summary.
This book covers basic concepts in population and quantitative genetics, including measuring selection on phenotypic traits.
This text introduces the principles of genetics and statistics that are relevant to population studies, and examines the forces affecting genetic variation from the molecular to the organismic level.
... 201 taxonomic congruence, 200–201 total evidence supermatrices approach, 201–202 T-Rex, 210 neighbor joining, ... for comparative genomics, 337–338 Venter, J. Craig, 6 VNTR, see Variable number of tandem repeat region Wallace, ...
Darwinian evolution in mendelian populations. Random genetic drift. Mutation and the neutral theory. Natural selection. Inbreeding and other forms of nonrandom mating. Population subdivision and migration. Molecular population genetics. Evolutionary...
Provides descriptions of the methods and tools used in molecular population genetics, which has combined advances in molecular biology and genomics with mathematical and empirical findings to uncover the history of natural selection and ...