Written primarily for students embarking on an undergraduate bioscience degree, this primer will review the essential biological concepts that underpin any programme of more advanced study and give early-stage undergraduates the opportunity to review topics about which they may feelunder-prepared or less confident.Genetic medicine has entered an era of rapid expansion. It is no longer just relevant to families affected by rare congenital disorders, but has the potential to affect the diagnosis and treatment of most common complex diseases.The successful application of new genetic science in the decades ahead will depend on the next generation of undergraduates or university applicants, who are now planning their careers as Biologists and Clinicians.This primer explores core concepts about heredity and genome analysis, illustratescurrent clinical practice with case-histories, and discusses the potentials and pitfalls of personalised medicine.
Stewart C, Kural D, Stromberg MP, et al: A comprehensive map of mobile element insertion polymorphisms in humans, PLoS Genet 7:e1002236, 2011. Sun JX, Helgason A, Masson G, et al: A direct characterization of human mutation based on ...
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In Genetic Medicine: A Logic of Disease, Barton Childs demonstrates that knowledge of the ways both genes and environment contribute to disease provides a rational basis for medical thinking.
The book focuses sharply on concepts that are most applicable to clinical practice. Ethics sections in each chapter discuss ethical issues facing today's practitioner, such as counseling, risk assessment, and testing.
Wang L, McLeod HL & Weinshilboum RM (2011) Genomics and drug response. ... Naldini L (2011) Ex vivo gene transfer and correction for cell-based therapies. ... Pearson H (2009) Human genetics: one gene, twenty years.
By integrating the classic principles of human genetics with modern molecular genetics, this medical reference book utilizes a variety of learning tools to help you understand a wide range of genetic disorders.
A thoughtful new look at the entwined histories of genetic medicine and eugenics, with probing discussion of the moral risks of seeking human perfection
Chapters can also be used as stand-alone learning aids for specific topics. Taken as a whole, this timely book delivers a complete overview of genetics in medicine.
92. 93. Chapter 16 • Fluorescence Patterns of Human Chromosomes • T. Patau, K., Smith, D. W., Therman, E., Inhorn, S. L., and Wagner, ... Serr, D. M., and Ismajovich, B. Determination of the primary sex ratio for human abortions.