Between 1935 and 1944, the field of microbiology, and by implication medicine as a whole, underwent dramatic advancement. The discovery of the extraordinary antibacterial properties of sulphonamides, penicillin, and streptomycin triggered a frantic hunt for more antimicrobial drugs that was to yield an abundant harvest in a very short space of time. By the early 1960s more than 50 antibacterial agents were available to the prescribing physician and, largely by aprocess of chemical modification of existing compounds, that number has more than tripled today. So used have we become to the ready availability of these relatively safe and highly effective 'miracle drugs' that it is now hard to grasp how they transformed the treatment ofinfection.This book provides the first comprehensive account of the development of antimicrobial agents of all kinds: antibacterial, antiviral, antifungal, antiprotozoal and anthelminthic compounds. It also offers a celebration of those involved with the agents that have surely led to the relief of more human and animal suffering than any other class of drugs in the history of medical endeavour.
New to this edition are chapters on aquaculture and on regulation of antibiotic use in animals.
This book contains comprehensive presentations of the mechanisms for both the antimicrobial actions and for the adverse clinical effects of these drugs.
Use of Antimicrobial Drugs in Office-based Practice: United States, 1980-81
This stimulating new edition of the well-respected title Biochemistry and Molecular Biology of Antimicrobial Drug Action primarily covers medically important antimicrobial agents, but also includes some compounds not in current medical use ...
Antimicrobial drugs are of central importance in combating illnesses such as typhoid, malaria, meningitis and influenza. This book describes the mode of action for the major classes of drugs.
Bond broken during the transpeptidation reaction associated with Crosslinking 25 Drugs that interfere with the ... of the spatial orientation of the principal atoms and polar groups in the B-lactam nucleus to one particular orientation ...
Although little data are available, it would seem likely (in general) that the former (a veterinary example is intramammary infusions) will expose ... Pharmacodynamic principles of antimicrobial therapy in the prevention of resistance.
This ? rst edition of Antimicrobial Drug Resistance grew out of a desire by the editors and authors to have a comprehensive resource of information on antimicrobial drug resistance that encompassed the current information available for ...
Tutorial Topics in Infection for the Combined Infection Training Programme is the first book covering the complete CIT curriculum.
This text is a reworking and expansion of 'Chemotherapy of Infection', book offers a thorough discussion on how the body handles antibiotics: their mechanisms of action, pharmacology, toxicity, and bacterial sensitivities.