Gillette (USA), C.D. Klaassen (USA), J.J. Kocsis, (USA), D.B. Menzel (USA), M. Mercier (Belgium), R.A. Neal (USA), F. Oesch (BRD), S. Orrenius (Sweden), H. Remmer (BRD), M. Roberfroid (Belgium), H. Vainio (Finland) and C.M. Witmer (USA), acting 'as a committee under G.G. Gibson (UK), D.J. Jollow (USA), D.V. Parke (UK) and R. Snyder (USA), co-chairmen, THE SECOND INTERNATIONAL SYMPOSIUM ON BIOLOGICAL REACTIVE INTERMEDIATES was convened at the University of Surrey in the United Kingdom on July 14-17, 1980. This volume derives directly from the presentations at the symposium. The University of Surrey, which is located in Guildford, Surrey, provided a congenial atmosphere for this conference and we would like to take this opportunity to thank the local organizing committee and especially Dr. G. Gordon Gibson, for all their efforts in both scientific and social arrangements. Special thanks are extended also to the graduate students of the Biochemistry Department (especially Ms. Tricia Breacker and Mr. Paul Tamburini) and to the conference secretaries who unstintingly gave of their time in a variety of roles to ensure the smooth functioning of the symposium. We wish to acknowledge the tireless efforts of the distinguished scientists who agreed to chair the sessions of the symposium: A. Hildebrandt (BRD), H. Remmer (BRD), L. Goldberg (USA), S. Orrenius (Sweden), H. Uehleke (BRD), J.R. Gillette (USA), C. Netter (BRD), M. Mercier (Belgium), F. Oesch (BRD), E. Boyland (UK), J.E. Gibson (USA), C.D. Klaassen (USA) and J.W. Gorrod (UK). The mounting of a large scale international symposium is fraught with many impediments, not the least of which are the financial and logistical problems of assembling a group of internationally distinguished scientists in one place at the same time. Success in such endeavors requires concerned and active sponsors. The three sponsoring
Among the results were a series of reports listed below, as well as the book for which this serves as the Preface. • Jollow, DJ., Kocsis, J.J., Snyder, R. and Vainio, H. (eds), Biological Reactive Intermediates: Formation, Toxicity and ...
This volume presents a discussion of the biological effects produced following the metabolism of xenobiotic chemicals to chemically reactive metabolites, i.e., toxic and carcinogenic effects, which have been the basis of all five earlier ...
Despite the antigenic similarity between the different P-450 isozymes, they do not all catalyze the same reaction, as seen in Table II using a substrate capable of oxidation to a number of isomeric and epimeric products, testosterone, ...
The Fourth International Symposium on Biological Reactive Intermediates was hosted by the Center for Toxicology at the University of Arizona and convened in Tucson, Arizona, January 14-17, 1990. Over 300 people attended.
The work of R. T. Williams, beginning in the late 1920s and early 1930s, marked the first concerted effort to understand the biotransformation of foreign chemicals in animals.
Proceedings of the International Symposium in Honor of the Late Professor Eberhard Steckhan Electrochemical Society. Organic and Biological Electrochemistry Division D. G. Peters. ELECTROCHEMICAL OXIDATION OF SILOLES : 2,3,4,5 ...
With contributions by world leaders in the field, the text covers a broad range of topics, including: A discussion of the relevent theory Ionization of DNA Nucleic acid sugar radicals Nucleobase radicals Halopyrimidines Oxidative, reductive ...
ACKNOWLEDGEMENTS Our work on photochemistry was started in collaboration with Massimo Olivucci, and the study of electron ... M. A. Robb, M. Garavelli, M. Olivucci, and F. Bernardi, A Computational Strategy for Organic Photochemistry, ...
Sulfur-Centered Reactive Intermediates in Chemistry and Biology