Protein Targeting reviews different aspects of protein targeting, including similarities and differences in the pathways involved. The early stages of protein export and secretion in prokaryotes and eukaryotes are examined, along with the targeting of mitochondrial and chloroplast proteins as well as some important differences in the biogenesis of the two organelles. Comprised of nine chapters, this book begins with an overview of terminology and basic principles of protein targeting, focusing on protein traffic in eukaryotic and bacterial cells. The reader is then introduced to the basic principles and techniques of protein targeting, including protein identification and posttranslational modification. Subsequent chapters deal with the early stages in the secretory pathway; later stages in the prokaryotic and eukaryotic secretory pathways; targeting of mitochondrial, chloroplast, and peroxisomal proteins; and targeting of nuclear proteins. The book also discusses endocytosis before concluding with a description of applications of protein targeting. This monograph will be of value to scientists and biotechnologists, as well as to students of cell biology, biochemistry, microbiology, and molecular biology.
In this volume, eminent experts in the field take the time to review the central aspects of mitochondrial biogenesis.
Numerous color illustrations complement the presentation of material. This book is an essential reference for anyone in biochemistry and protein science, as well as an excellent textbook for advanced students in these and related fields.
In this updated volume, experts from around the world provide the latest protocols for isolating different organelles and the localization of particular proteins using a variety of methods such as light, confocal, and electron microscopy.
This text reviews our current state of knowledge regarding the interaction of proteins at the membrane interface and the assembly of proteins into biological membranes, before proceeding to look at targeting pathways in both prokaryotic and ...
Protein targeting is the study of how newly synthesized proteins reach their ultimate destination. Proteins may be targeted into an intracellular organelle such as the nucleus, mitochondria, or rough endoplasmic...
This book provides a comprehensive overview of recent developments in the fast moving field of protein transport across and into intracellular membranes.
This book presents an overview of the most relevant protein knockdown techniques.
In addition, the book examines the full range of complex biological systems and their interrelationship with chemistry, from the interaction of biological response modifiers with proteins to the chemical biology of cell surface ...
Proteins act as macromolecular machinery that mediate many diverse biological processes - the molecular mechanisms of this machinery has fascinated biologists for decades.
Eukaryotic cells are composed of diverse subcompartments, or organelles, that each have unique functions and distinct protein compositions.