Get a quick, expert overview of the many key facets of pediatric cancer genetics with this concise, practical resource by Dr. Nathaniel H. Robin and Meagan Farmer, MS, CGC, MBA. Ideal for pediatric oncologists and all providers who care for children, this easy-to-read reference addresses the remarkable potential of genetic testing as well as the complexities of choosing the correct test, understanding the results, and counseling the family. Features a wealth of information on pediatric cancer genetics, including the epidemiology and biology of cancer and the genetic evaluation process and role of genetic counselors. Highlights examples of syndromes that present in childhood and increase susceptibility to cancer. Discusses the genetic evaluation process in context of the multidisciplinary care of children with cancer. Considers the ethical and legal issues of genetic testing in children and provides illustrative case examples. Consolidates today’s available information and guidance in this timely area into one convenient resource.
This volume elaborates on the research and clinical implications of the hereditary and molecular basis of childhood cancers.
This book introduces readers to the study of how genes, singly and in combination with each other and the environment, affect health and behavior. It provides family-focused perspectives relating to genetic counseling and education.
Diagnostic, biological, and therapeutic issues are integrated into each tumor-specific chapter, with evidence supporting the current rationales for risk stratification and the development of novel therapies.
Barnett RM., Borras EN, Samadder J, Vilar E. Chemoprevention in Hereditary Colorectal Cancer Syndromes. Cham: Springer; 2018. 70. Nielsen M, Morreau H, Vasen HF, Hes FJ. MUTYH-associated polyposis (MAP). Crit Rev Oncol Hematol.
Genetic mutations in cancer susceptibility genes: a family history of cancer. Cancer patients in a pediatric intensive care unit: a single center experience. The impact of childhood cancer on the quality of life among healthy siblings.
Chepuri NB, Strouse PJ, Yanik GA. CT of renal lymphoma in children. Am J Roentgenol 2003;180:429–431. Durno CA, Gallinger S. Genetic predisposition to colorectal cancer: new pieces in the pediatric puzzle. J Pediatr Gastroenterol Nutr ...
Tools such as sidebars, key concept summaries, a glossary, and acronym and abbreviation definitions make this book highly accessible to researchers from several fields associated with cancer genomics.
... BER genes are associated with cancer, and these genes are epigenetically silenced in some tumors. It is likely that this and other repair systems function less efficiently with age and contribute to cancer risk (Lahtz and Pfeifer, ...
In this eBook, we described the accomplishments, collaborative projects and future initiatives in the field of breast cancer genetic predisposition.
Anticipate and Communicate is the Bioethics Commission's sixth major report.