Provides a concise introduction to the chemistry of therapeutically active compounds, written in a readable and accessible style. The title begins by reviewing the structures and nomenclature of the more common classes of naturally occurring compounds found in biological organisms. An overview of medicinal chemistry is followed by chapters covering the discovery and design of drugs, pharmacokinetics and drug metabolism, The book concludes with a chapter on organic synthesis, followed by a brief look at drug development from the research stage through to marketing the final product. The text assumes little in the way of prior biological knowledge. relevant biology is included through biological topics, examples and the Appendices. Incorporates summary sections, examples, applications and problems Each chapter contains an additional summary section and solutions to the questions are provided at the end of the text Invaluable for undergraduates studying within the chemical, pharmaceutical and life sciences.
The primary objective of this 4-volume book series is to educate PharmD students on the subject of medicinal chemistry. The book set serves as a reference guide to pharmacists on aspects of chemical basis of drug action.
Whether you are just starting your education toward a career in a healthcare field or need to brush up on your organic chemistry concepts, this book is here to help you navigate medicinal chemistry.
Medicinal Chemistry: Fundaments presents the cycle of the life of drugs, their physico-chemical properties, and consequences that arise in development.
Burger's Medicinal Chemistry and Drug Discovery, Academic Version
Uttamsingh, V.; Gallegos, R.; Liu, J. F.; Harbeson, S. L.; Bridson, G. W.; Cheng, C.; Wells, D. S.; Graham, P. B.; Zelle, R.; Tung, ... Egger, H.; Itterly, W.; John, V.; Shimanskas, C.; Stancato, F.; Kapoor, A. Drug Metab. Dispos.
From the reviews of the First Edition: "It contains a wealth of information in a compact form" ANGEWANDTE CHEMIE, INTERNATIONAL EDITION "Medicinal Chemistry is certainly a text I would chose to teach from for undergraduates.
NEW TO THIS EDITION Updated throughout with the latest descoveries Five new chapters covering * the molecular structure of receptors and the mechanisms of signal transduction *combinatorial synthesis * the role of computers in drug design * ...
This fourth edition has been revised and updated to include new chapters on:* chromatographic methods of analysis * medicinal chemistry: the science of rational drug design.Essentials of Pharmaceutical Chemistry will be of particular ...
If the properties are weak, the candidate will have a high risk of failure or be less desirable as a drug product. This book is a tool and resource for scientists engaged in, or preparing for, the selection and optimization process.
Alberts, A. W.; Chen, J.; Kuron, 6.; Hunt, V.; Huff, J.; Hoffman, C.; Rothrock, J.; Lopez, M.; Joshua, H.; Harris, E.; Patchett, A.; Monaghan, R.; ... (a) Stokker, G. E.; Rooney, C. S.; Wiggins, J. M.; Hirschfield, J. J. Org. Chem.