Antibacterial Agents: Chemistry, Mode of Action, Mechanisms of Resistance and Clinical Applications
- ISBN-10
- 0470972440
- ISBN-13
- 9780470972441
- Series
- Antibacterial Agents
- Category
- Science
- Pages
- 378
- Language
- English
- Published
- 2012-07-23
- Publisher
- John Wiley & Sons
- Authors
- Paul W. Groundwater, Rosaleen Anderson, Adam Todd
Description
Antibacterial agents act against bacterial infection either by killing the bacterium or by arresting its growth. They do this by targeting bacterial DNA and its associated processes, attacking bacterial metabolic processes including protein synthesis, or interfering with bacterial cell wall synthesis and function. Antibacterial Agents is an essential guide to this important class of chemotherapeutic drugs. Compounds are organised according to their target, which helps the reader understand the mechanism of action of these drugs and how resistance can arise. The book uses an integrated lab–to–clinic approach which covers drug discovery, source or synthesis, mode of action, mechanisms of resistance, clinical aspects (including links to current guidelines, significant drug interactions, cautions and contraindications), prodrugs and future improvements. Agents covered include: agents targeting DNA – quinolone, rifamycin, and nitroimidazole antibacterial agents agents targeting metabolic processes – sulfonamide antibacterial agents and trimethoprim agents targeting protein synthesis – aminoglycoside, macrolide and tetracycline antibiotics, chloramphenicol, and oxazolidinones agents targeting cell wall synthesis – –Lactam and glycopeptide antibiotics, cycloserine, isonaizid, and daptomycin Antibacterial Agents will find a place on the bookshelves of students of pharmacy, pharmacology, pharmaceutical sciences, drug design/discovery, and medicinal chemistry, and as a bench reference for pharmacists and pharmaceutical researchers in academia and industry.
Get the book
Other editions
-
- 2012-07-23
- 363 pages
- Paperback
- John Wiley & Sons
-
- 2012-05-30
- 376 pages
- Ebook
- John Wiley & Sons
Similar books
-
Chemistry: An Introduction to General, Organic and Biological Chemistry
By Karen C. TimberlakeThis new edition introduces more problem-solving strategies and new conceptual and challenge problems. Also, each Chapter Review has been enhanced with Learning Goals to reinforce the mastery of concepts for students.
-
Chemistry: An Introduction to General, Organic, and Biological Chemistry
By Karen TimberlakeThis laboratory manual contains 42 experiments for the standard sequence of topics in general, organic, and biological chemistry.
-
Basic Chemistry
By Karen C. TimberlakeThe book guides students through basic chemistry problem solving with engaging visuals and a focus on developing the math skills necessary to be successful in the course.
-
General, Organic, and Biological Chemistry: Structures of Life, eBook, Global Edition
By Karen C. TimberlakeThe full text downloaded to your computer With eBooks you can: search for key concepts, words and phrases make highlights and notes as you study share your notes with friends eBooks are downloaded to your computer and accessible either ...
-
Basic Chemistry
By Karen C. Timberlake, William E. TimberlakeBasic Chemistry
-
Basic Chemistry, Books a la Carte Edition
By Karen C. TimberlakeBasic Chemistry, Books a la Carte Edition
-
Essential Laboratory Manual for General, Organic and Biological Chemistry
By Karen C. TimberlakeEssential Laboratory Manual for General, Organic and Biological Chemistry
-
Basic Chemistry, Global Edition
By Karen C. Timberlake, Bill TimberlakeThe main objective in writing this text is to make the study of chemistry an engaging and a positive experience for students by relating the structure and behaviour of matter to real life.
-
General, Organic, and Biological Chemistry: An Integrated Approach
By Karen C. Timberlake, Laura D. Frost, Todd S. DealThe eText pages look exactly like the printed text, and include powerful interactive and customization functions. This is the product access code card for MasteringChemistry with Pearson eText and does not include the actual bound book.
-
Chemistry: An Introduction to General, Organic, and Biological Chemistry
By Karen C. TimberlakeHealth, Environmental, and Green Chemistry Notes throughout the text relate chemistry chapters to real-life topics in health, the environment, and medicine that are interesting and motivating to students.