Comprehensive, advanced treatment of nature and source of inherited characteristics, with treatment of mathematical techniques. Mendelian populations, mutations, polymorphisms, genetic demography, much more. Emphasizes interpretation of data in relation to theoretical models.
As human genetics and genomics research often employs tools and approaches derived from population genetics, this book helps users understand the basic principles of these tools.
Due to technological and methodological advances, progress has been made at determining the architecture of complex traits. Split in three parts, the book starts with the basics, followed by more advanced and current research.
Coop G, Pickrell JK, Novembre J, Kudaravalli S, LiJ, Absher D, Myers RM, Cavalli-Sforza LL, Feldman MW, Pritchard JK (2009) The role of geography in human adaptation. PLoS Genetics 5(6):e1000500. doi:10.1371/journal/pgen.1000500.
Genetics of Human Populations
In human DNA approximately 0.08% of the nucleotide base pairs varies among individuals and thus populations genetics has been trying to establish why this is so.
This is the first reference book of its kind to bring together data from these diverse sets of markers for understanding evolutionary histories and relationships of modern humans in a single volume.
( a ) D = Divergence P = Polymorphism s = Synonymous a = Amino acid ( b ) Adh D. simulans vs D. yakuba P = 0.005 ( c ) ... McDonald and Kreitman realized that if polymorphisms within species are faithfully transformed into divergence ...
Natural Selection in Human Populations: The Measurement of Ongoing Genetic Evolution in Contemporary Societies
This book tells the emerging story of our often surprising ancestry - the extraordinary ancient migrations and mixtures of populations that have made us who we are.
Tzetis M, Hanson M, Kalaydjieva L, Glavac D, Gasparini P, Kanavakis E, Claustres M, Kambouris M, Ostrer H, Duff G, ... Wagner CL, Greer FR, Section on Breastfeeding and Committee on Nutrition (2008) Prevention of rickets and vitamin D ...