This book, a compilation by experts in the field, is designed to provide an introduction to the area of medicinal inorganic chemistry and to summarize current, state-of-the-art developments in the field. Medicinal inorganic chemistry represents a key thrust area in medicine and biological inorganic chemistry. It is one of great current excitement and achievement. The field of metals in medicine represents an approximate $3 billion dollar a year industry, with successes in the area of Tc- and Gd-based imaging agents and Pt-based cancer therapeutics being major contributors to this bottom line. It has become increasingly apparent, however, that metal-based pharmaceuticals can play a prominent role in areas outside of imaging and oncology, including in those associated with the diagnosis and treatment of metabolism- and genetic disorders, cardiovascular disease, gene therapy, inflammation, reperfusion injury, stroke, diabetes, ALS, malaria, and neurological disease to name but a few. A objective of this book, therefore, is to highlight these opportunities for future advances and to foster further interactions between those working in the metal-based drug development, including imaging agents, and those engaged in the more classic pharmaceutical industries.
This book serves to fill an important niche, bridging bioinorganic and medicinal chemistry and will undoubtedly be of use to senior undergraduates and postgraduates, as well as being an invaluable asset for teachers and researchers in the ...
Written for students of pharmacy and pharmacology, pharmaceutical sciences, medicinal chemistry and other health-care related subjects, this accessible text introduces chemical principles with relevant pharmaceutical examples rather than as ...
Inorganic Medicinal and Pharmaceutical Chemistry
Ligand Design in Medicinal Inorganic Chemistry presents the state-of-the-art in ligand design for medicinal inorganic chemistry applications.
The book provides a detailed state-of-the-art overview of inorganic chemistry applied to medicinal chemistry and biology.
This book gives a comprehensive overview about medicinal inorganic chemistry.
Thoroughly revised and restructured to reflect significant research activity and advances, this new edition contains extensive updates and new pedagogical features while retaining the popular feature boxes and end-of-chapter problems of the ...
This book is organized into 12 important chapters that focus on the progress made by metal-based drugs as anticancer, antibacterial, antiviral, anti-inflammatory, and anti-neurodegenerative agents, as well as highlights the application ...
Medicinal Chemistry, Volume 75, the latest release in the Advances in Inorganic Chemistry series, presents timely and informative summaries on current progress in a variety of subject areas.
Emerging trends in medicinal chemistry efforts are moving towards the more targeted approach and this is being revolutionized and enhanced by genomics and proteomics.