Toxicological Risk Assessment of Chemicals: A Practical Guide
- ISBN-10
- 0849372658
- ISBN-13
- 9780849372650
- Category
- Medical
- Pages
- 448
- Language
- English
- Published
- 2008-02-21
- Publisher
- CRC Press
- Authors
- Elsa Nielsen, Grete Ostergaard, John Christian Larsen
Description
Unlike many existing books on toxicology that cover either toxicity of a particular substance or toxicity of chemicals on particular organ systems, Toxicological Risk Assessment of Chemicals: A Practical Guide lays out the principle activities of conducting a toxicological risk assessment, including international approaches and methods for the risk assessment of chemical substances. It illustrates each step in the process: hazard identification, a dose response assessment, and exposure assessment. The book also summarizes the basic concepts of interaction of chemicals in mixtures and discusses various approaches to testing such mixtures. Features: Addresses standards from all international regulatory agencies Presents the steps in risk assessment, including hazard identification, exposure assessment, and risk characterization Covers the assessment of multiple chemical exposures or chemical mixtures Contains data from both human and animal studies Explains the linearized multi-stage mathematical model widely used by the US EPA for characterizing
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