Ebola and Marburg Viruses: Molecular and Cellular Biology

Ebola and Marburg Viruses: Molecular and Cellular Biology
ISBN-10
0954523237
ISBN-13
9780954523237
Category
Science
Pages
392
Language
English
Published
2004
Publisher
Garland Science
Authors
Hans-Dieter Klenk, Heinz Feldmann

Description

The Ebola and Marburg viruses are a pair of filoviruses that are among the most lethal hemorrhagic viruses on the planet. The authors present a review of past and current research into these pathogens, including 12 papers addressing the structure of the viral proteins; genomic replication; molecular mechanisms of entry; pathogenesis in nonhuman primates, guinea pigs, and mice; virus modulation of innate immunity; and cellular and molecular mechanisms of Ebola pathogenicity and related approaches to vaccine development.

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