This volume covers the latest techniques that study the synthesis of melatonin, its receptor function, and its effects at the cellular and systemic level. The chapters are organized into three parts. Part One describes methods for the detection of melatonin and its biological derivatives in various biological samples, the manipulation of melatonin synthesis by the pineal gland in animals, and the principal source of melatonin in mammals. Part Two explores methods to measure the biological effects and consequences of melatonin binding to high-affinity G protein-coupled receptors. Part Three describes methods to measure the physiological effects that are regulated by melatonin in animals, particularly in rodent models. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Melatonin: Methods and Protocols is a valuable resource for any researcher interested in investigating melatonin, from its production to its mechanisms of action and systemic effects.
This important book presents a full spectrum of research on melatonin and is destined to become an essential reference for anyone interested in melatonin.
In this book, Dr. Fauteck summarizes critical information related to the necessity of maintaining regular biological rhythms and describes the pathological consequences of circadian rhythm disturbances.
Bartsch, H., Bartsch, C, Simon, W. E., et al. "Antitumor Activity of the Pineal Gland: Effect of Unidentified Substances Versus the Effect of Melatonin." Oncology 49:27-30. 1992. Beitins, I. Z., Barkan, A., Klibanski, A., et al.
Sleep is one of the most important factors in good health—and this guide to melatonin gives you an all-natural way to get that much-needed rest.
... F., Castrogiovanni, P., Melatonin in psychiatric disorders: A review on the melatonin involvement in psychiatry. Front Neuroendocrinol, 22, 18-32, 2001. Shiloh, R., Nutt, D., Weizman, A., Atlas of Psychiatric Pharmacotherapy, ...
Now people are venturing out and are looking for ways to reduce the risk. Wearing masks, social distancing, washing hands, all help. This book offers another way: Maximizing natural melatonin and taking melatonin by mouth.
Discusses the hormone melatonin and its use as a supplement to fight insomnia and jet lag, improve mood and energy, fight diseases such as cancer, and increase longevity.
Scientific evidence now supports various health benefits of melatonin.
Melatonin possesses antioxidant activity, and many of its proposed therapeutic or preventive uses are based on this property. This book presents a wide spectrum of research on melatonin.
Melatonin: Therapeutic Value and Neuroprotection explores melatonin's neuroprotective effects and discusses the therapeutic potential of melatonin and melatonin agonists in treating neurodegenerati