Engineering and Biological Applications of Antibodies Against Small Molecules
- ISBN-10
- 1109946163
- ISBN-13
- 9781109946161
- Category
- Monoclonal antibodies
- Pages
- 335
- Language
- English
- Published
- 2006
- Author
- Gunnar J. F. Kaufmann
Description
Chapter Three describes the application of an anti-trans-stilbene antibody. Fluorescently-labeled DNA polymers are valuable molecular probes that are widely used in basic science and medicine. Here, we describe the synthesis of a stilbene-tethered deoxyadenosine triphosphate analog, its enzymatic incorporation into DNA to yield an antibody-activatable blue fluorescent DNA polymer and hybridization studies of the modified DNA polymer with chromosomal DNA.
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