A Handbook for DNA-Encoded Chemistry: Theory and Applications for Exploring Chemical Space and Drug Discovery
- ISBN-10
- 1118487680
- ISBN-13
- 9781118487686
- Category
- Science
- Pages
- 480
- Language
- English
- Published
- 2014-04-28
- Publisher
- John Wiley & Sons
- Authors
- Jr., Robert A. Goodnow
Description
This book comprehensively describes the development and practice of DNA-encoded library synthesis technology. Together, the chapters detail an approach to drug discovery that offers an attractive addition to the portfolio of existing hit generation technologies such as high-throughput screening, structure-based drug discovery and fragment-based screening. The book: Provides a valuable guide for understanding and applying DNA-encoded combinatorial chemistry Helps chemists generate and screen novel chemical libraries of large size and quality Bridges interdisciplinary areas of DNA-encoded combinatorial chemistry – synthetic and analytical chemistry, molecular biology, informatics, and biochemistry Shows medicinal and pharmaceutical chemists how to efficiently broaden available “chemical space” for drug discovery Provides expert and up-to-date summary of reported literature for DNA-encoded and DNA-directed chemistry technology and methods
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Other editions
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- 2014-04-10
- 480 pages
- Ebook
- John Wiley & Sons
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