Lysosomes: Biology, Diseases, and Therapeutics
- ISBN-10
- 1118645154
- ISBN-13
- 9781118645154
- Series
- Lysosomes
- Category
- Medical
- Pages
- 561
- Language
- English
- Published
- 2016-06-27
- Publisher
- John Wiley & Sons
- Authors
- Frederick R. Maxfield, James M. Willard, Shuyan Lu
Description
Discussing recent findings, up-to-date research, and novel strategies, the book integrates perspectives from pharmacology, toxicology, and biochemistry to illustrate the potential of lysosomes in drug discovery and development. • Explores basic principles and properties of lysosomes that allow them to act as regulators of cell metabolism, therapeutic targets, and sites for activation of drug conjugates • Discusses the role of lysosomes in metabolism, drug targeting, apoptosis, cancer, aging, inflammation, autophagy, metabolism, toxicity, and membrane repair • Introduces new pathways in therapeutic development and new mechanisms in drug development
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Other editions
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- 2017-08-30
- 176 pages
- Paperback
- BoD – Books on Demand
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