Inorganic Chemical Biology: Principles, Techniques and Applications
- ISBN-10
- 111868415X
- ISBN-13
- 9781118684153
- Category
- Science
- Pages
- 432
- Language
- English
- Published
- 2014-04-14
- Publisher
- John Wiley & Sons
- Author
- Gilles Gasser
Description
Understanding, identifying and influencing the biologicalsystems are the primary objectives of chemical biology. From this perspective, metal complexes havealways been of great assistance to chemical biologists, for example, in structural identificationand purification of essential biomolecules, for visualizing cellular organelles or to inhibitspecific enzymes. This inorganic side of chemical biology, which continues to receive considerableattention, is referred to as inorganic chemical biology. Inorganic Chemical Biology: Principles, Techniques andApplications provides a comprehensive overview of the current and emerging role of metal complexes inchemical biology. Throughout all of the chapters there is a strong emphasis on fundamentaltheoretical chemistry and experiments that have been carried out in living cells or organisms. Outlooksfor the future applications of metal complexes in chemical biology are also discussed. Topics covered include: • Metal complexes as tools for structural biology • IMAC, AAS, XRF and MS as detection techniques for metals inchemical biology • Cell and organism imaging and probing DNA using metal andmetal carbonyl complexes • Detection of metal ions, anions and small molecules usingmetal complexes • Photo-release of metal ions in living cells • Metal complexes as enzyme inhibitors and catalysts inliving cells Written by a team of international experts, Inorganic ChemicalBiology: Principles, Techniques and Applications is a must-have for bioinorganic,bioorganometallic and medicinal chemists as well as chemical biologists working in both academia and industry.
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Other editions
-
- 2014-06-23
- 437 pages
- Paperback
- John Wiley & Sons
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