Molecular Biology of Cancer

Molecular Biology of Cancer
ISBN-10
1135321604
ISBN-13
9781135321604
Series
Molecular Biology of Cancer
Category
Medical
Pages
269
Language
English
Published
2004-06-02
Publisher
Taylor & Francis
Authors
Fiona Macdonald, Christopher Ford, Alan Casson

Description

It has been realized for many years that cancer has a genetic component and at the level of the cell it can be said to be a genetic disease. In 1914, Boveri suggested that an aberration in the genome might be responsible for the origins of cancer. This was subsequently supported by the evidence that cancer, or the risk of cancer, could be inherited; that mutagens could cause tumors in both animals and humans; and that tumors are monoclonal in origin, that is, the cells of a tumor all show the genetic characteristics of the original transformed cell. It is only in recent years that the involvement of specific genes has been demonstrated at the molecular level. Molecular Biology of Cancer. Second edition is now in a larger format that has been extensively revised and covers heredity cancer, microarray technology and increased study of childhood cancers. --

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