This volume contains the papers presented at IALCCE 2018, the Sixth International Symposium on Life-Cycle Civil Engineering, to be held in Ghent, Belgium, October 28-31, 2018. It consists of a book of extended abstracts and a DVD with full papers including the Fazlur R. Khan lecture, keynote lectures, and technical papers from all over the world. All major aspects of life-cycle engineering are addressed, with special focus on structural damage processes, life-cycle design, inspection, monitoring, assessment, maintenance and rehabilitation, life-cycle cost of structures and infrastructures, life-cycle performance of special structures, and life-cycle oriented computational tools. The aim of the editors is to provide a valuable source for anyone interested in life-cycle of civil infrastructure systems, including students, researchers and practitioners from all areas of engineering and industry.