Nonlinear Models for Repeated Measurement Data

Nonlinear Models for Repeated Measurement Data
ISBN-10
1351428144
ISBN-13
9781351428149
Category
Mathematics
Pages
360
Language
English
Published
2017-11-01
Publisher
Routledge
Author
Marie Davidian

Description

Nonlinear measurement data arise in a wide variety of biological and biomedical applications, such as longitudinal clinical trials, studies of drug kinetics and growth, and the analysis of assay and laboratory data. Nonlinear Models for Repeated Measurement Data provides the first unified development of methods and models for data of this type, with a detailed treatment of inference for the nonlinear mixed effects and its extensions. A particular strength of the book is the inclusion of several detailed case studies from the areas of population pharmacokinetics and pharmacodynamics, immunoassay and bioassay development and the analysis of growth curves.

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