Medicinal Chemistry begins with the history of the field, starting from the serendipitous use of plant preparations to current practice of design- and target-based screening methods. Written from the perspective of practicing medicinal chemists, the text covers key drug discovery activities such as pharmacokinetics and patenting, as well as the classes and structures of drug targets (receptors, enzymes, nucleic acids, and protein-protein and lipid interactions) with numerous examples of drugs acting at each type. Selected therapeutic areas include drugs to treat cancer, infectious diseases, and central nervous system disorders. Throughout the book, historical and current examples illustrate the progress to market and case studies explore the applications of concepts discussed in the text. Each chapter features a Journal Club, as well as review and application questions to enhance and test comprehension. This textbook is ideal for upper-level undergraduates and graduate students taking a one-semester survey course on medicinal chemistry and/or drug discovery, as well as scientists entering the pharmaceutical industry.
Rang, H. P., Dale, M. M., Ritter, J. M., Flower, R. Rang & Dale's Pharmacology, 6th Edition. Churchill Livingstone: New York, 2007. ... Shargel, L., Wu-Pong, S., Yu, A. B. C. Applied Biopharmaceutics and Pharmacokinetics, 5th Edition.
From the reviews of the First Edition: "It contains a wealth of information in a compact form" ANGEWANDTE CHEMIE, INTERNATIONAL EDITION "Medicinal Chemistry is certainly a text I would chose to teach from for undergraduates.
We therefore decided to evaluate future analogs as pure P1 isomers. ... We therefore decided to investigate new P10 derivatives of analog 74 that lacked double bond and made new analogs as a single diastereomer at P1 (Table 13).
Whether you are just starting your education toward a career in a healthcare field or need to brush up on your organic chemistry concepts, this book is here to help you navigate medicinal chemistry.
This book aims to be their practical handbook - a complete guide to the drug discovery process.
This is where Small Molecule Medicinal Chemistry: Strategies and Technologies comes in, helping medicinal chemists and colleagues in related disciplines to identify and progress new innovative small molecules as efficiently as possible.
The Textbook of Medicinal Chemistry is a much-awaited masterpiece in its arena.
"Frontiers in Medicinal Chemistry" is an Ebook series devoted to the review of areas of important topical interest to medicinal chemists and others in allied disciplines.
The market-leader in medicinal chemistry: clear, supportive, and practical.
This is a carefully curated compilation of writing from global experts using their broad experience of medicinal chemistry, project leadership and drug discovery and development from an industry, academic and charity perspective to provide ...