Comparative effectiveness research (CER) is the generation and synthesis of evidence that compares the benefits and harms of alternative methods to prevent, diagnose, treat, and monitor a clinical condition or to improve the delivery of care (IOM 2009). CER is conducted to develop evidence that will aid patients, clinicians, purchasers, and health policy makers in making informed decisions at both the individual and population levels. CER encompasses a very broad range of types of studies—experimental, observational, prospective, retrospective, and research synthesis. This volume covers the main areas of quantitative methodology for the design and analysis of CER studies. The volume has four major sections—causal inference; clinical trials; research synthesis; and specialized topics. The audience includes CER methodologists, quantitative-trained researchers interested in CER, and graduate students in statistics, epidemiology, and health services and outcomes research. The book assumes a masters-level course in regression analysis and familiarity with clinical research.
This User’s Guide is a resource for investigators and stakeholders who develop and review observational comparative effectiveness research protocols.
Comparative Effectiveness Research: Evidence, Medicine, and Policy provides the first complete account of how — and why — the federal government decided to make comparative effectiveness research (CER) an important feature of health ...
Clinical research presents health care providers with information on the natural history and clinical presentations of disease as well as diagnostic and treatment options.
This book is a compilation of the writings of several experts in the field and their collaborators.
This book is a compilation of the writings of several experts in the field and their collaborators.
This book will serve as a vital resource for both sponsors and producers of systematic reviews of comparative effectiveness research.
The Handbook of Health Services Research is a reference for all aspects of the field of health services and outcomes research.
Integrating multiple perspectives from academia, industry, and regulatory agencies, this comprehensive volume has been fully revised and updated to provide first-class guidance for anyone in need of up-to-date information on all aspects of ...
What are best practices in key questions and how these subgroups have been identified? 3. How have systematic reviews dealt with clinical heterogeneity in the review process? a.
Providing a unified framework on the principles and applications of the science of health disparities research, this important volume: Defines the field of health disparities science and suggests new directions in scholarship and research ...