Reflecting more than a decade's worth of changes, Animal Models in Toxicology, Second Edition is a practical guide to the common statistical problems encountered in toxicology and the methodologies that are available to solve them. The book presents a historical review of the use of animal models and an overview of broad considerations of me
The book concludes with an overview of the increasingly complex laws and regulations that govern how laboratory animals are obtained, maintained, and utilized, and an appendix that provides a quick guide to commercial sources of laboratory ...
This edition includes five new chapters. The first of these provides specific and detailed guidance on the humane, efficient, and effective performance of necropsies for laboratory animals.
In: Lee DHK, Falk HL, Murphy SD, Geiger SR, eds. Handbook of Physiology, Section 9, Reactions to Environmental Agents. Bethesda, MD: American Physiology Society, 1977:349–374. 28. Reinhardt MC. Macromolecular absorption of food antigens ...
This book explores the factors which are critical in the selection of an appropriate animal species for toxicology studies and the subsequent extrapolation of the data to humans.
While there are differences that have to be accounted for, Berridge said there is a logical rationale for the dependence on animals as a surrogate for the human system. Citing a study that investigated the concordance of drug toxicity ...
The reader can find under this one volume virtually all types of existing and emerging tumor models in use by the research community. This book provides a deeper insight on how these newer models could de-risk modern drug discovery.
This fourth edition will be useful all over the world as a textbook for laboratory animal science courses for postgraduate and undergraduate students and as a handbook for scientists who work with animals in their research, for university ...
Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics.
Scientific and Ethical Issues National Research Council, Policy and Global Affairs, Science, Technology, and Law Program, ... He is a member of the Institute of Medicine and the National Academies Science, Technology, and Law Panel.
Improving the Utility and Translation of Animal Models for Nervous System Disorders: Workshop Summary also identifies methods to facilitate development of corresponding animal and clinical endpoints, indentifies methods that would maximize ...