Molecular Biology of Chromosome Function
- ISBN-10
- 1461236525
- ISBN-13
- 9781461236528
- Category
- Science
- Pages
- 431
- Language
- English
- Published
- 2012-12-06
- Publisher
- Springer Science & Business Media
- Author
- Kenneth W. Adolph
Description
Chromosomes have structure, determined by the interactions of proteins with DNA, and chromosomes have functions, in particular, replication of DNA and transcription of messenger RNA. Chromosome structure and function are not separate topics, since chromosome organization pro foundly influences the activity of the genome in replication and transcrip tion. This is especially clear for higher cells, including human cells, in which chromatin fibers are created by the binding of histone proteins to the DNA, and folding of the fibers produces mitotic chromosomes and interphase nuclei. The intricate organization of DNA in higher cells is now recognized as being closely involved with genome activity. Many fundamental results have originated from studies of bacterial and viral systems, which have been systems of choice because of their less complex life cycles. The processes of replication and transcription show differences between the higher and simpler systems (e. g. , different enzymes and protein factors are involved). But the parallels are as striking as the differences in detail. Even for bacteria and viruses, a full understanding of these processes will require integrating the results of molecular biology with those of structural biology and cell biology. Three important subjects are covered in this volume: DNA replication and recombination, gene transcription, and chromosome organization. The sections dealing with replication and transcription examine recent results obtained by applying the techniques of molecular biology and biochemistry. Eukaryotic, prokaryotic, and viral systems are discussed.
Get the book
Similar books
-
Molecular Biology of Chromosome Function
By Kenneth W. AdolphMolecular Biology of Chromosome Function
-
Chromosomes: Organization and Function
By Adrian T. SumnerTausta, S.L., Turner, L.R., Buckley, L.K. & Klobutcher, L.A. (1991) High fidelity developmental excision of Tec1 transposons and internal eliminated sequences in Euplotes crassus. Nucleic Acids Research 19, 3229–3236.
-
Chromosome Biology
By R. Morris, Rudi Appels, Bikram S. GillThis is true in the plant arena, and it is becoming increasingly true in animal studies, where chromosomes are more difficult to work with.
-
Molecular Biology of the Cell
By Bruce AlbertsThe book contains color illustrations and charts; and the included CD-ROM contains dozens of video clips, animations, molecular structures, and high-resolution micrographs. Annotation copyrighted by Book News Inc., Portland, OR.
-
Human Chromosomes
By Eeva Therman, Orlando J. MillerThe fourth edition of this well-known text provides students, researchers and technicians in the area of medicine, genetics and cell biology with a concise, understandable introduction to the structure and behavior of human chromosomes.
-
Chromosome Structure and Function
By Andreas Houben'Chromosome Structure and Function' will be an invaluable resource for undergraduate and postgraduate students in fields such as plant and animal sciences, genetics, and molecular biology.
-
Chromatin: Structure and Function
By Alan P. Wolffeoccurs during the repair of UV-induced photoproducts (Smerdon and Lieberman, 1978). There is an initial rapid increase in nuclease sensitivity over repair patches coupled to a loss of the 10-11 bp modulation of DNase I cleavage (Smerdon ...
-
Molecular Genetics
By Herbert TaylorOrganized into seven chapters, this volume begins with an overview of the general properties of type I and type II restriction enzymes, basic aspects of restriction enzyme technology, and applications of restriction enzyme technology to the ...
-
Human Molecular Genetics
By Jamie Benton &However, all of the genes together are only a small part of DNA code. The 30,000 odd genes in human DNA might only make up 4% of human DNA. This book presents a view in depth of the principal aspects of life science.
-
The Role of Chromosomes in Development
By Michael LockeThis book will be of interest to developmental biologists and embryologists.