Chemical Induction of Cancer: Structural Bases and Biological Mechanisms Volume IIIA deals with the organic and biochemical principles behind cancer. This volume contains the continuation of Volume IIA, which tackles structure-activity relationships of chemical carcinogens, the effect of chemical reactivity, molecular geometry, and metabolism on carcinogenic activity. Under this is non-conjugated organic compounds. The text is recommended for doctors, organic chemists, and biochemists with an advanced knowledge in biochemistry and organic chemistry and would like to know more the biochemical processes of cancer.
Hollinger, M. A., Giri, S. N., Alley, M., Budd, E. R., and Hwang, F.: Drug Metab. Dispos. 2, 521 (1974). Hollinger, M.A., and Giri, S. N.: Res. Commun. Chem. Pathol. Pharmacol. 26, 609 (1979). Castro, J. A., D'Acosta, N., De Ferreyra, ...
Chemical Induction of Cancer: Structural Bases and Biological Mechanisms
The ultimate goal of QSAR analysis should be to predict not only whether a chemical is an animal carcinogen but also the likelihood of whether the ... IIIB, Aliphatic and Polyhalogenated Carcinogens, Academic Press, New York, 1985. 10.
Hollinger , M. A. , Giri , S. N. , Alley , M. , Budd , E. R. , and Hwang , F .: Drug Metab . Dispos . 2 , 521 ( 1974 ) . 252. Hollinger , M. A. , and Giri , S. N .: Res . Commun .
Krogh, P., Axelsen, N. H., Elling, F., Gyrd-Hansen, N., Hald, B., Hyldaard-Jensen, J., 97. 98. 99. Zucker, P. F., Chan, A. M., and Archer, M. C.: Proc. Am. Assoc. Cancer Res. 25, 81 (1984). Murphy, M. L., and Karnofsky, D. A.: Cancer 9, ...
319-351 Fishbein, L., Industrial mutagens and potential mutagens, I. Halogenated aliphatic derivatives, Mutation Res. 32 (1976) 267-308 Van Duuren, B. L., Chemical structure, reactivity, and carcinogenicity of halohydrocarbons, Environ.
The potency of a fraction may be influenced to a great extent by long-chain aliphatic and aromatic hydrocarbons, e.g. n-dodecane, dodecylbenzene, ... TABLE III Carcinogenicity of Petroleum Carcinogens* Cocarcinogens Inhibitors ...
Such chemical (non-enzymic) reactions, for example, account for the rearrangement of aliphatic carcinogen epoxides that are formed in vivo, and for interactions of reactive carcinogen intermediates with cellular macromolecules.
IIIC, Natural, Metal, Fiber and Macromolecular carcinogens. San Diego, Calif: Academic Press, 1988. 13. CIoannides, DFV Lewis, J Trinick, S Neville, NN Sertkaya, M Kajbaf, JW Gorrod. A rationale for the non-mutagenicity of 2- and ...
The presence of chemicals in our environment is a subject of intense interest owing to the many potential adverse health effects to humans following exposure to these chemicals.