Praise for the first edition "This book captures, in a very accessible way, a growing body of literature on the structure, function and motion of proteins [...] [This is] a superb publication that would be very useful to undergraduates, graduate students, postdoctoral researchers, and instructors involved in structural biology or biophysics courses or in research on protein structure-function relationships." --David Sheehan, ChemBioChem, 2011 "Introduction to Proteinsis an excellent, state-of-the-art choice for students, faculty, or researchers needing a monograph on protein structure. [...] this is an immensely informative, thoroughly researched, up-to-date text, with broad coverage and remarkable depth. Introduction to Proteinswould provide an excellent basis for an upper-level or graduate course on protein structure, and a valuable addition to the libraries of professionals interested in this centrally important field." --Eric Martz, Biochemistry and Molecular Biology Education, 2012 Introduction to Proteinsshows how proteins can be analyzed in multiple ways. It refers to the roles of proteins and enzymes in diverse contexts and everyday applications, including medical disorders, drugs, toxins, chemical warfare, and animal behavior. New features in the thoroughly-updated second edition: A brand-new chapter on enzymatic catalysis, describing enzyme biochemistry, classification, kinetics, thermodynamics, mechanisms, and applications in medicine and other industries. These are accompanied bymultiple animationsof biochemical reactions and mechanisms,accessible via embedded QR codes(can be viewed by smartphones) An in-depth discussion of G-protein-coupled receptors (GPCRs) A wider-scale description of biochemical and biophysicalmethods for studying proteins, including fully accessible internet-based resources, such as databases and algorithms Animations of protein dynamicsand conformational changes, accessible via embedded QR codes Additional features Extensive discussion of the energetics of protein folding, stability and interactions A comprehensive view of membrane proteins, with emphasis on structure-function relationship Coverage of intrinsically unstructured proteins, providing a complete, realistic view of the proteome and its underlying functions Exploration of industrial applications of protein engineering and rational drug design Approximately 300 color images Downloadable solutions manual available at www.crcpress.com applications in medicine and other industries. These are accompanied bymultiple animationsof biochemical reactions and mechanisms,accessible via embedded QR codes(can be viewed by smartphones) An in-depth discussion of G-protein-coupled receptors (GPCRs) A wider-scale description of biochemical and biophysicalmethods for studying proteins, including fully accessible internet-based resources, such as databases and algorithms Animations of protein dynamicsand conformational changes, accessible via embedded QR codes Additional features Extensive discussion of the energetics of protein folding, stability and interactions A comprehensive view of membrane proteins, with emphasis on structure-function relationship Coverage of intrinsically unstructured proteins, providing a complete, realistic view of the proteome and its underlying functions Exploration of industrial applications of protein engineering and rational drug design Approximately 300 color images Downloadable solutions manual available at www.crcpress.com tability and interactions A comprehensive view of membrane proteins, with emphasis on structure-function relationship Coverage of intrinsically unstructured proteins, providing a complete, realistic view of the proteome and its underlying functions Exploration of industrial applications of protein engineering and rational drug design Approximately 300 color images Downloadable solutions manual available at www.crcpress.com
Human cells produce at least 30,000 different proteins.
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This new edition gives an up-to-date account of the principles of protein structure, with examples of key proteins in their biological context, illustrated in colour to illuminate the structural principles described in the text.
The desire to understand protein structure has been given new impetus by the explosive growth of biotechnology and the important role of proteins, natural and modified, in this technology. Protein...
Larrabee, J. A. & Choi, S. Fourier transform infrared spectroscopy. Methods Enzymol. ... Ludwig, S., Pleschka, 8., Planz, O., & Wolff, T. Influenza virus induced signalling cascades: targets for antiviral therapy? Trends Mol.
This book serves as an introduction to protein structure and function.
The building blocks.
Starting by describing the structure of proteins and explaining how these structures can be studied, this book goes on to illustrate the wide range of protein functions by showing how the shape of a protein is intimately linked to its ...
The appendices are designed to be consulted throughout the section on protein dynamics without breaking the deductive flow of the logic in the central section of the book.
The book provides an introduction to the fundamentals of amino acids and proteins as well as the composition of food. It then delves into the molecular biology of the cell and genetic machinery and its function.