Studies that are unimpeachably thorough, non-political, unbiased, and properly designed... These are the standards to which everyone in clinical research aspires. Yet, the difficulties in designing trials and interpreting data are subtle and ever present. The new edition of Clinical Trials in Oncology provides a concise, nontechnical, and now thoroughly up-to-date review of methods and issues related to clinical trials. The authors emphasize the importance of proper study design, analysis, and data management and identify the major pitfalls that are seemingly inherent in these processes. This edition includes a new section that describes recent innovations in Phase I designs. Another new section on microarray data examines the challenges presented by massive data sets and describes approaches used to meet those challenges. As always, the authors use clear, lucid prose and a multitude of real-world trials as examples to convey the principles of successful trials without the need for a strong statistics or mathematics background. Although the book focuses on cancer trials, the issues and concepts are important in any clinical setting. Clinical Trials in Oncology, Second Edition works to improve the mutual understanding by clinicians and statisticians of the principles of clinical trials and helps them avoid the many hazards that can jeopardize the success of a trial.
The book discusses clinical trials from start to finish focusing on real-life examples in the development, design and analysis of clinical trials.
Guidance for industry. Good pharmacovigilance practices and pharmacoepidemiologic assessment; March 2005 (20 pp.). 1Kotterman MA, Schaffer DV. Engineering adeno-associated viruses for clinical gene CLINICAL TRIALS 568 25.
Peto R., Pike M. C., Armitage P., Breslow N. E., Cox D. R., Howard S. V., Mantel N., McPherson K., Peto I., and Smith P. G. Design and analysis of randomized clinical trials requiring prolonged observation of each patient.
Jobling R. Therapeutic research into psoriasis: patients' perspectives, priorities and interests. In: Rawlins M, Littlejohns P, eds, Delivering Quality in the NHS 2005. Oxford: Radcliffe Publishing (2005) 53–6. 2. McKenna KE, Stern RS.
Completely revised while keeping the features that made the first edition a bestseller, this is the best single source for up-to-date statistical approaches to research in clinical medicine.
Updated and expanded, this Second Edition of Essentials of Clinical Radiation Oncology continues to provide a succinct and effective review of the most important studies in the field.
"A comprehensive reference for professionals providing up-to-date oncology nutrition practice recommendations, the latest nutrition assessment tools, current knowledge, and support and resources"--
Genetic Susceptibility to Lung Cancer Ann G. Schwartz, Joan E. vinorelbine plus cisplatin for advanced non-small-cell lung cancer: the TAX 326 study group. J Clin Oncol. 2003;21:3016–3024. Belani CP, von Pawel J, Pluzanska A, et al.
Written by an author team with extensive experience in conducting clinical trials, this book: Provides comprehensive coverage of randomised clinical trials, ranging from basic to advanced Features several new chapters, updated case studies ...
Brownlee KA : Statistical theory and methodology in science and engineering , New York , 1965 , John Wiley & Sons . 21. ... DeSilva RA , Hennekcns CH , Lown B , Casscells W : Lignocaine prophylaxis in acute myocardial infarction : an ...