Leukemia and Lymphoma: Detection of Minimal Residual Disease
- ISBN-10
- 1592593186
- ISBN-13
- 9781592593187
- Category
- Medical
- Pages
- 257
- Language
- English
- Published
- 2002-10-21
- Publisher
- Springer Science & Business Media
- Authors
- Theodore F. Zipf, Dennis A. Johnston
Description
In Leukemia and Lymphoma: Detection of Minimal Residual Disease, hands-on experts describe and discuss the minimal residual disease (MRD) methods they have successfully pioneered for leukemias and lymphomas. They apply reverse transcription PCR (RT-PCR) to acute myeloid leukemia (AML), chronic myelogenous leukemia (CML), and acute promyelocytic leukemia (APL). Other PCR methods are used for Non-Hodgkin's Lymphoma and for the monitoring of follicular lymphoma. Additional chapters address the use of real-time quantitative PCR (RQ-PCR), the emergent method of choice, in patients with acute lymphoblastic leukemia (ALL), the evaluation of MRD techniques in clinical trials, and the application of flow cytometry techniques.
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