Clinical Applications of PCR
- ISBN-10
- 159745074X
- ISBN-13
- 9781597450744
- Category
- Science
- Pages
- 200
- Language
- English
- Published
- 2008-02-04
- Publisher
- Springer Science & Business Media
- Author
- Y. M. Dennis Lo
Description
In this updated second edition, leading researchers apply molecular diagnostics to the many recent advances that have occurred in polymerase chain reaction( PCR)-based technologies. Highlights include real-time PCR, which allows the technique to be performed in a quantitative manner with improved sensitivity, robustness, and resilience to carryover contamination, mass spectrometric analysis of nucleic acids, and circulating cell-free nucleic acids in plasma. The authors apply these innovations to a broad spectrum of applications, including gene expression, methylation, trace molecule, gene dosage, and single cell analysis.
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