Apoptosis is the regulated form of cell death. It is a complex process defined by a set of characteristic morphological and biochemical features that involves the active participation of affected cells in a self-destruction cascade. This programmed cell death plays a critical role in physiological functions such as cell deletion during embryonic development, balancing cell number in continuously renewing tissues and immune system development. Additionally, a dysregulation of apoptosis is underlying in numerous pathological situations such as Parkinson, Alzheimer's disease and cancer.A number of studies have pointed out an association between consumption of fruits and vegetables, and certain beverages such as tea and wine, which are rich in polyphenols, with reduced risk of chronic diseases, including cancer. Apoptosis is also the regulatory mechanism involved in the removal of unnecessary cells during development and in tissue homeostasis in a wide range of organisms from insects to mammals. This book deals with cell apoptosis regulation and environmental factors.
These volumes teach readers to think beyond apoptosis and describes all of the known processes that cells can undergo which result in cell death This two-volume source on how cells dies is the first, comprehensive collection to cover all of ...
It is a complex process defined by a set of characteristic morphological and biochemical features that involves the active participation of affected cells in a self-destruction cascade. This book presents research from around the world.
This book is a collection of selected and relevant research, concerning the developments within the Cell Death field of study.
This is quite in contrast to the loss of cell contents typical of necrosis. The caspases, the family of intracellular cysteine proteases associated with apoptosis, are responsible for the stereotypical m- phological changes.
This is the second edition of the comprehensive, concise summary of apoptosis research. It covers the major concepts, molecular architecture, the biochemical pathways, and pathophysiological significance of apoptosis.
Looks at programmed cell death in the context of the normal life and death cycle of cells and multicelluar organisms and summarizes the latest techniques for the study of cells.
Begley, C.G., Lopez, A.F., Nicola, N.A., Warren, D.J., Vadas, M.A., Sauderson,C.J. & Metcalf, D. 1986 Purified colony-stimulating factors enhance the survival of human neutrophils and eosinophils in vitro: a rapid and sensitive ...
[ 2 ] Parkin , D.M .; Bray , F .; Ferlay , J. and Pisani , P. ( 2001 ) . Estimating the world cancer burden : Globocan 2000. Int . J. Cancer , 94 , 153-156 . [ 3 ] Parkin , D.M .; Bray , F .; Ferlay , J. and Pisani , P. ( 2005 ) .
In this second edition of Douglas Green's essential book on cell death, Green retains the bottom-up approach of the first edition, starting with the enzymes that carry out the execution (caspases) and their cellular targets before examining ...
This book provides studies in the field of apoptosis research.