Although benzodiazepines are among the most commonly prescribed medications, owing to their roles in multiple areas of therapeutic action as anxiolytics, sedative hypnotics, anticonvulsants and muscle relaxants, they are also highly addictive. Long-term use can lead to dependency, rebound anxiety, memory impairment and withdrawal. In this book, the authors discuss the abuse and therapeutic uses, pharmacology and health effects of benzodiazepine. Topics include the effects of benzodiazepine during prolonged administration and under conditions of stress; anxiolytic-like effect and excessive side actions produced by benzodiazepines in the elderly; risk factors for benzodiazepine dependence in women with major depression or anxiety disorders; flumazenil slow-infusion in the treatment of high dose benzodiazepine dependence; benzodiazepine withdrawal syndrome; and encephalopathies related to exogenous or endogenous benzodiazepines.
Benzodiazepine Dependence, Toxicity, and Abuse provides clinicians with a review of the available information on the potential hazards of benzodiazepine treatment and offers suggestions for the rational prescription of these medications.
Discusses endogenous benzodiazepine-like substances – what do they do, do they affect the anti-anxiety drugs and their adverse effects?
Designed to help adults suffering from panic disorder who wish to discontinue anxiety medication, this program is designed for mental health professional treating panic disorder patients wishing to discontinue anxiety medication.
Niznik , H.B. , Burnham , W.M. & Kish , S.J. ( 1984 ) . Benzodiazepine receptor binding following amygdala - kindled convulsions : Differing results in washed and unwashed brain membranes . Journal of Neurochemistry , 43 , 1732–6 .
The Benzodiazepines: Current Standards for Medical Practice
The story of the benzodiazepines is a fascinating one: the synthesis of a long series of inert compounds and the abandonment of the project: months later, the renewal of the project and the discovery that this compound R05-0690 (Librium ®) ...
This book is the first to bring to light and discuss the largely unrecognized and enigmatic problem of an exceedingly prolonged withdrawal syndrome from benzodiazepines that can persist for months or years in susceptible patients, and the ...
Among the most successful drugs ever introduced, benzodiazepines still dominate the tranquilizer market. However, they are perceived today to have major problems: they produce dose-related subjective sedation; psychomotor, cognitive, and...
Benzodiazepines are powerful psychoactive drugs which were first approved for use in the 1960s. They have sedative/hypnotic, anxiolytic and anticonvulsive activity. The most common indication for their use is insomnia,...
This book offers a broad range of recent developments and detailed coverage of the synthesis and biological activities of the drugs based on benzodiazepine and benzothiazepine matrixes, and is an ideal reference guide to researchers working ...