The Organic Chemistry of Isotopic Labelling
- ISBN-10
- 1788018184
- ISBN-13
- 9781788018180
- Category
- Science
- Pages
- 200
- Language
- English
- Published
- 2019-04-05
- Publisher
- Royal Society of Chemistry
- Author
- James R Hanson
Description
The chemical synthesis of isotopically labelled compounds is a pre-requisite for many chemical, biochemical and medicinal investigations. The constraints imposed by the requirements for regiospecific labelling and, in some instances, the time-scale of the synthesis often lead to quite different synthetic strategies to those that are used for the unlabelled material. Whilst there are many specialist papers, reviews and long books devoted to particular isotopes, there is no currently available short introductory book devoted to the organic chemistry of isotopic labelling. The aim of this book is to introduce research workers to a variety of methods that have been used to achieve these synthetic labelling objectives before exploring a particular method in detail. It covers a number of different isotopes and the methods that have been used to introduce them into organic compounds. Labelling methods also provide useful undergraduate teaching examples of modern synthetic reactions and their stereochemical consequences using relatively simple substrates. The book will therefore have a wider appeal than just those involved in using isotopes in research such as environmental and pharmaceutical chemists as well as organic chemists.
Get the book
Other editions
Similar books
-
New Discoveries in Isotopic Labelling of Organic Molecules & Flow Chemistry - a Useful Technique in Organic Synthesis
By Søren Christian Schou, Københavns Universitet. Farmaceutiske FakultetNew Discoveries in Isotopic Labelling of Organic Molecules & Flow Chemistry - a Useful Technique in Organic Synthesis
-
Organic Reaction Mechanisms: 40 Solved Cases
By Mar Gómez Gallego, Miguel A. SierraThe book makes an excellent primer for advanced undergraduates in chemistry who are preparing for exams and is also useful for graduate students and instructors.
-
The Poet who Forgot
By Cathy ColeThe aim of this book is to introduce research workers to a variety of methods that have been used to achieve these synthetic labelling objectives before exploring a particular method in detail.
-
Lipidomics: Comprehensive Mass Spectrometry of Lipids
By Xianlin HanThis book is focused on the mass spectrometry of lipids that has occurred in these years. The content of this book is classified into four sections: introduction, characterization, quantification, and application.
-
Seminars in Organic Synthesis: XXXIV A. Corbella Summer School
By Enrico MarcantoniDiscusses some of the major developments that have taken place in the field of organic synthesis. This volume serves as a useful reference source for students and researchers in both academia and industry.
-
Isotopes, Essential Chemistry and Applications: The Lectures Delivered at a Review Symposium
By Chemical Society, University of SurreyIsotopes, Essential Chemistry and Applications: The Lectures Delivered at a Review Symposium
-
Reactive Drug Metabolites
By Dennis A. Smith, Amit S. Kalgutkar, Deepak DalvieSince the authors carefully develop the knowledge needed, from fundamental considerations to current industry standards, no degree in pharmacology is required to read this book, making it perfect for medicinal chemists without in-depth ...
-
Isotope Dilution Mass Spectrometry
By José Alonso, Pablo GonzálezThis unique book covers all the theoretical and practical aspects of Isotope Dilution Mass Spectrometry (IDMS).
-
The Investigation of Organic Reactions and Their Mechanisms
By Howard MaskillThe book covers basic aspects such as product analysis, kinetics, catalysis, and investigation of reactive intermediates.
-
Bioconjugate Techniques
By Greg T. HermansonAnal. Bioanal. Chem. 397, 2401–2407. Olekhnovich, I.N., Kadner, R.J., 2002. Mutational scanning and affin- ity cleavage analysis of UhpA-binding sites in the Escherichia coli uhpT promoter. J. Bacteriol. 184, 2682–2691. Osborn ...