Computational Methods for Understanding Bacterial and Archaeal Genomes

Computational Methods for Understanding Bacterial and Archaeal Genomes
ISBN-10
1860949827
ISBN-13
9781860949821
Category
Medical
Pages
473
Language
English
Published
2008
Publisher
World Scientific
Authors
Ying Xu, J. Peter Gogarten

Description

Over 500 prokaryotic genomes have been sequenced to date, and thousands more have been planned for the next few years. While these genomic sequence data provide unprecedented opportunities for biologists to study the world of prokaryotes, they also raise extremely challenging issues such as how to decode the rich information encoded in these genomes. This comprehensive volume includes a collection of cohesively written chapters on prokaryotic genomes, their organization and evolution, the information they encode, and the computational approaches needed to derive such information. A comparative view of bacterial and archaeal genomes, and how information is encoded differently in them, is also presented. Combining theoretical discussions and computational techniques, the book serves as a valuable introductory textbook for graduate-level microbial genomics and informatics courses.

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