Tobacco smoking is a major risk factor for a number of chronic diseases, including a variety of cancers, lung disease and damage to the cardiovascular system. The World Health Organization recently calculated that there were 6 million smoking-attributable deaths per year and that this number is due to rise to about eight million per year by the end of 2030. Recent work has demonstrated that habitual smoking in adults is not only associated with a range of health problems, but may also contribute to a number of neurocognitive deficits, including deficits in memory and attention. One area of growing concern is the health and neurocognitive consequences of exposure to second-hand smoke or “passive smoking” (where a non-smoker inhales another person’s smoke, mainly in the form of side-stream smoke). In terms of tackling smoking-related problems, there has been a rise in the amount and range of smoking cessation and interventions techniques, including the emergence of e-cigarettes as one of the most popular forms of nicotine replacement therapies. The present book comprises a collection of manuscripts discussing (1) the impact of active and passive smoking upon health and neurocognitive function, (2) smoking cessation techniques and interventions used to tackle smoking-related problems, and (3) a critical consideration of current issues surrounding the use of e-cigarettes as nicotine-replacement therapy. This collection of papers includes empirical, theoretical, and review papers. This Research Topic demonstrates the broad nature of research currently being undertaken in this field and should pave the way for future work.
[PubMed] Madden, K.; Mills, S.; Dibaj, S.; Williams, J.L.; Liu, D.; Bruera, E. Methadone as the Initial Long-Acting Opioid in Children with Advanced Cancer. J. Palliat. Med. 2018. [CrossRef][PubMed] Madden, K.; Park, M.; Liu, D.; ...
In addition, pancreatic stellate cells lead to the resistance to chemotherapy and radiation therapy. Pancreatic stellate cells attract the researchers as a novel therapeutic target of pancreatic cancer.
Communication between them has been informal and relatively limited in scope. This situation could be improved by developing a comprehensive approach to the collection and dissemination of information.
Now, many of tau researchers are seeking a “toxic” form of tau protein. Moreover, it was suggested that a “toxic” tau was capable to seed aggregation of native tau protein and to propagate in a prion-like manner.
The major function of γδ T-cells resides in local immunosurveillance and immune defense against infection and malignancy. This is supported by the identification of ligands that are selectively recognized by the γδ TCR.
In the past quarter of a century monocarboxylate transporters (MCTs) were identified and localized in both cellular and mitochondrial membranes. A lactate receptor has been identified.
Many forms of ischemic conditioning (including classical, pharmacological, and remote conditioning) converge on signaling pathways that either inhibit cell death or activate endogenous cell survival maintenance programs.
The Centers for Disease Control and Prevention currently recommends 30 min of moderate- to high-intensity exercise for at least 5 days a week for all healthy individuals (DHHS, 2002). In addition to significantly lowering causes of ...
The illustrative material with original photographs and drawings highlighting some pathogenetic concepts are keystones of this book.
In this special issue of Diagnostics, expert contributors have produced up-to-date research studies and reviews on various topics related to the diagnosis of dementia and cognitive impairment.