This book focuses on the emerging non-invasive imaging technique of Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO). FLIO reveals unique information on retinal diseases, ranging from age-related macular degeneration and vascular diseases to hereditary retinal dystrophies. Fluorescence lifetimes enable the evaluation of disease progression before irreversible structural changes occur. The image acquisition is suitable for diagnostic purposes and follow-up examinations to investigate the natural course of disease, and to monitor the effects of possible therapies. This book fills the gap between available literature and gives state-of-the-art guidance on the principles of the FLIO technique, image acquisition, and data analysis. Written by a team of expert leaders within this field, this book will be relevant for scientists and clinicians with an interest in ophthalmoscopy.
This open access book provides a comprehensive overview of the application of the newest laser and microscope/ophthalmoscope technology in the field of high resolution imaging in microscopy and ophthalmology.
A companion Website will offer the fully searchable text and an image bank.
Moussa K, Lee JY, Stinnett SS, et al. Spectral domain optical coherence tomographydetermined morphologic predictors of agerelated macular degenerationassociated geographic atrophy progression. Retina 2013;33(8):1590–1599.
... lifetime imaging ophthalmoscopy: a novel way to assess macular telangiectasia Type 2. Ophthalmol Retina. (2018) 2:587–98. doi: 10.1016/j.oret.2017.10.008 471. Vitale AS, Sauer L, Modersitzki NK, Bernstein PS. Fluorescence Lifetime Imaging ...
The book starts with an introduction by Dr. Wolfgang Kaiser, pioneer of nonlinear optics and ends with the chapter on clinical multiphoton tomography, the novel high resolution imaging technique.
The aim of this volume is to provide a wide range of techniques and aspects of mouse retinal phenotyping and characterization.
Modern Tools for Time-Resolved Luminescence Biosensing and Imaging
The second edition of OCT and Imaging in Central Nervous System Diseases offers updated state-of-the-art advances using optical coherence tomography (OCT) regrading neuronal loss within the retina.
This book provides an essential overview of existing state-of-the-art quantitative imaging methodologies and protocols (intensity-based ratiometric and FLIM/ PLIM).
... imaging of retinal cell apoptosis by confocal scanning laser ophthalmoscopy and its role in glaucoma. Front Neurol. 2018;9:338. 212. Lakowicz JR, Szmacinski H, Nowaczyk K, Berndt KW, Johnson M. Fluorescence lifetime imaging. Anal ...