This book constitutes the refereed proceedings of the 6th International Conference on Innovative Technologies and Learning, ICITL 2023, held in Porto, Portugal, during August 28-30, 2023. The 64 full papers included in this book were carefully reviewed and selected from 147 submissions. They cover a wide range of many different research topics, such as: artificial intelligence in education; computational thinking in education; design and framework of learning systems; pedagogies to innovative technologies and learning; STEM/STEAM education; VR/AR/MR/XR in education; and application and design of innovative learning software.