The Networking of Chaperones by Co-chaperones: Control of Cellular Protein Homeostasis
- ISBN-10
- 3319117319
- ISBN-13
- 9783319117317
- Category
- Medical
- Pages
- 276
- Language
- English
- Published
- 2014-12-08
- Publisher
- Springer
- Authors
- Gregory Lloyd Blatch, Adrienne Lesley Edkins
Description
Co-chaperones are important mediators of the outcome of chaperone assisted protein homeostasis, which is a dynamic balance between the integrated processes of protein folding, degradation and translocation. The Networking of Chaperones by Co-chaperones describes how the function of the major molecular chaperones is regulated by a cohort of diverse non-client proteins, known as co-chaperones. The second edition includes the current status of the field and descriptions of a number of novel co-chaperones that have been recently identified. This new edition has a strong focus on the role of co-chaperones in human disease and as putative drug targets. The book will be a resource for both newcomers and established researchers in the field of cell stress and chaperones, as well as those interested in cross-cutting disciplines such as cellular networks and systems biology.
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